Gan Lu Xiao Du Dan

Classical TCM Formula Profile

Part of the HJMEDICAL TCM Discovery Center

甘露消毒丹 · Gān Lù Xiāo Dú Dān

A classical epidemic formula for damp-heat with fever, oppression and turbid damp signs.

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Quick Facts

Formula Category
Dampness-Draining Formulas
Primary Pattern
Damp-Heat
Primary Function
Resolve damp, clear heat, ventilate Qi, resolve toxin
Primary Therapeutic Principle
Clear damp-heat, resolve turbidity and open the Qi mechanism
Classical Source
Qing dynasty formulary
Available as Granules
Yes

Formula Overview

A classical epidemic formula for damp-heat with fever, oppression and turbid damp signs.

Therapeutic Principle

Traditionally selected for epidemic or diffuse damp-heat with fever and turbid damp, rather than early mild damp-warmth, pure urinary lin, or Liver-Gallbladder damp-heat alone.

Composition: Sovereign, Minister, Assistant, Envoy

Every herb in the formula, grouped by the job it does in the classical hierarchy.

佐/使Assistant & EnvoyTreats accompanying patterns, harmonises the whole
石菖蒲Shi Chang Pu6g
Grassleaf Sweetflag Rhizome
  • moves qi and remove dampness refresh the spleen and harmonize the center
This combination promotes qi movement to facilitate the removal of dampness.; Helps the chief to clear heat and remove dampness.
川貝母Chuan Bei Mu6g
Sichuan Fritillaria
  • clears heat and resolves toxins
  • dissipates nodules and relieves swelling
  • benefits the throat and relieves pain
Treats accompanying patterns and supports the chief medicinals.
木通Mu Tong6g
Akebia Stem
  • clears heat removes dampness and relieves strangury
Treats accompanying patterns and supports the chief medicinals.
藿香Huo Xiang6g
Agastache / Patchouli
  • clears heat and resolves toxins
  • dissipates nodules and relieves swelling
  • benefits the throat and relieves pain
Treats accompanying patterns and supports the chief medicinals.
射干She Gan6g
Belamcanda Rhizome
  • clears heat and resolves toxins
  • dissipates nodules and relieves swelling
  • benefits the throat and relieves pain
Treats accompanying patterns and supports the chief medicinals.
連翹Lian Qiao9g
Forsythia Fruit
  • clears heat and resolves toxins
  • dissipates nodules and relieves swelling
  • benefits the throat and relieves pain
Treats accompanying patterns and supports the chief medicinals.
薄荷Bo He6g
Mentha / Peppermint
  • clears heat and resolves toxins
  • dissipates nodules and relieves swelling
  • benefits the throat and relieves pain
Treats accompanying patterns and supports the chief medicinals.
白豆蔻Bai Dou Kou6g
Round Cardamom
  • clears heat and resolves toxins
  • dissipates nodules and relieves swelling
  • benefits the throat and relieves pain
Treats accompanying patterns and supports the chief medicinals.

Classical Composition

  • Talcum (Hua Shi) 15 liang (450g)
  • Scutellariae Radix (Huang Qin) 10 liang (300g)
  • Artemisiae Capillaris Herba (Yin Chen) 11 liang (330g)
  • Acori Tatarinowii Rhizoma (Shi Chang Pu) 6 liang (180g)
  • Fritillariae Cirrhosae Bulbus (Chuan Bei Mu) 5 liang (150g)
  • Akebiae Caulis (Mu Tong) 5 liang (150g)
  • Pogostemonis Herba (Huo Xiang) 4 liang (120g)
  • Forsythiae Fructus (Lian Qiao) 4 liang (120g)
  • Amomi Fructus Rotundus (Bai Dou Kou) 4 liang (120g)
  • Menthae Haplocalycis Herba (Bo He) 4 liang (120g)
  • Belamcandae Rhizoma (She Gan) 4 liang (120g)

Dosages follow the classical source and are shown for study, not as a prescription.

Related Conditions

Related Health Topics

Actions

  • Drains dampness and removes turbidity
  • clears heat and resolves toxins.

Indications

  • Gan Lu Xiao Du Dan is indicated for damp-warmth and seasonal epidemic.
  • It is a pattern with equal dampness and heat pathogens in the qi level.
  • The symptoms are fever and fatigue, chest distress and abdominal distension, aching pain of limbs, throat pain, yellow skin and eyes, maxillofacial swelling, thirst, scanty and dark urine, diarrhea, and turbid strangury.

Tongue & pulseThe tongue coating may be either white, thick and greasy or yellow and dry. The pulse is either soggy and rapid or slippery and rapid.

Traditional Pathogenesis

Cause & mechanism

  • This formula is applied to patterns that have equal dampness and heat.
  • Fever, aching pain of limbs and fatigue are caused by heat steaming dampness.
  • Chest distress and abdominal distension are caused by dampness accumulation in middle jiao.
  • Yellow skin and eyes are caused by damp-heat steaming in the liver and gallbladder.
  • Thirst, throat pain, and maxillofacial swelling are caused by heat attacking the upper jiao.
  • Scanty dark urine, diarrhea, and turbid strangury are caused by damp-heat pouring downward.

Clinical presentation

  • A tongue with thick, white, and greasy or dry, yellow coating is a sign of damp-heat stagnation in the qi level.

Treatment strategy

  • The therapeutic methods are to drain dampness and remove turbidity and to clear heat and resolve toxins.

How does this formula compare?

Compare Gan Lu Xiao Du DanSan Ren TangBa Zheng SanLong Dan Xie Gan Tang
Primary Function Resolve damp, clear heat, ventilate Qi, resolve toxinDiffuse Qi, resolve damp, clear heat gentlyClear heat, drain damp, promote urination, unblock linClear Liver Fire, drain Damp-Heat
Formula Category Dampness-Draining FormulasDampness-Draining FormulasHeat-Clearing FormulasHeat-Clearing Formulas
Typical TCM Pattern Damp-HeatDamp-HeatDamp-HeatLiver Fire
Main Conditions Fever·Damp-Heat Constitution·Poor AppetiteFever·Poor Appetite·Damp-Heat Constitution·Chest TightnessFrequent Urination·Abdominal Pain·Dry Mouth & Throat·ConstipationBitter Taste in Mouth·Liver Qi Stagnation·Damp-Heat Constitution
Main Herbs Talcum·Virgate Wormwood·Scutellaria / Baikal Skullcap·Grassleaf Sweetflag Rhizome·Sichuan FritillariaBitter Apricot Kernel·Round Cardamom·Coix Seed / Job's Tears·Magnolia Bark·Pinellia RhizomePlantago Seed·Dianthus·Knotweed·Talcum·Gardenia FruitGentian Root·Scutellaria / Baikal Skullcap·Gardenia Fruit·Alisma Rhizome·Akebia Stem
Classical Source Qing dynasty formularyWen Bing Tiao Bian (Wu Jutong, 1798)Tai Ping Hui Min He Ji Ju Fang (Song dynasty)Yi Fang Ji Jie (Analytic Collection of Medical Formulas, Wang Ang, Qing dynasty)

Clinical Perspective

Gan Lu Xiao Du Dan, San Ren Tang, Ba Zheng San and Long Dan Xie Gan Tang all address damp-heat. San Ren Tang is early damp-warmth with Qi obstruction; Ba Zheng San focuses on lower-jiao damp-heat lin syndrome; Long Dan Xie Gan clears Liver-Gallbladder damp-heat. Gan Lu Xiao Du Dan is broader for epidemic damp-heat with fever, oppression and turbid damp signs.

Clinical Differentiation

  • Gan Lu Xiao Du Dan is a common formula used in the summer for damp-warmth and seasonal epidemic with equal amounts of dampness and heat.
  • Doctor Wang Shi-xiong named it as the principal formula for treating damp-warmth.
  • This clinical pattern is marked by feverish sensation and aching pain of limbs, thirst, dark urine, throat pain, yellow skin, white and greasy, or light yellow tongue coating.

Safety notes: This formula is not applicable for damp-heat invading ying level, marked by delirious speech and crimson tongue.

For educational reference only, based on traditional pattern differentiation — not a substitute for professional advice.

Frequently Asked Questions

What are the actions of Gan Lu Xiao Du Dan?
Gan Lu Xiao Du Dan has the actions of resolving Dampness and transforming turbidity, clearing Heat, and resolving Toxicity. It is the classic formula for Damp-Warmth or seasonal epidemic patterns in which Dampness and Heat are equally severe and remain in the Qi level.
Which modern diseases is Gan Lu Xiao Du Dan suited to?
Modern TCM clinical practice commonly applies it to individuals whose pattern differentiation falls within Damp-Heat (equal Damp and Heat), including acute viral hepatitis with jaundice, acute gastroenteritis, cholecystitis, leptospirosis, certain cases of mumps or tonsillitis with Damp-Heat features, and other summer-autumn epidemic or infectious conditions matching this pattern.
Is Gan Lu Xiao Du Dan suitable for improving fever with fatigue, chest oppression, sore throat, and jaundice?
For presentations of fever with body heaviness and fatigue, chest oppression and abdominal distension, aching limbs, sore or swollen throat, possible yellowing of the skin or eyes, thirst, dark scanty urine, a white greasy or yellow tongue coating, and a soft or slippery rapid pulse — in those whose pattern differentiation confirms Damp-Warmth with equal Damp and Heat in the Qi level — TCM commonly applies Gan Lu Xiao Du Dan as an adjunct. It cannot replace standard medical treatment of infectious or hepatic diseases.
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Medical Disclaimer

For general TCM education only — not medical advice. Consult a qualified TCM practitioner or licensed healthcare provider before use, especially if pregnant, nursing, on medication, or managing a chronic condition.

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