Fruits and seedsDampness-drainingHoveniae Semen

Zhi Ju Zi (Raisin Tree Seed)

A practical guide to Zhi Ju Zi: what it is, how Traditional Chinese Medicine uses it, the classical formulas it appears in, and who should be careful with it.

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Last reviewed Oct 29, 2026

Quick Facts

Latin NameHoveniae Semen
Chinese Name & Pinyin 枳椇子 · Zhi Ju Zi
Medicinal PartFruits and seeds
The itemZhi Ju Zi is the ripe fruit stalk cluster of Hovenia dulcis, used raw or stir-fried. Ge Hua is not this herb. It usually goes into decoctions or light teas.
Nature and channelsSweet, sour, neutral. Enters the Stomach and Spleen. It resolves alcohol toxin, relieves thirst and vexation, clears damp-heat, and frees urination.
Pharmacopoeia lineResolves alcohol toxin. Relieves thirst and vexation. Clears damp-heat and facilitates urination. Traditionally used for drunkenness with dizziness and nausea, damp-heat stagnation, and scanty urine.
Pattern cuesHangover with dizziness and nausea. Sticky mouth and heavy body. Scanty dark urine.
In this articleZhi Ju Zi versus Ge Hua. Resolving alcohol versus draining damp-heat. Why deficiency-cold spleen is a poor match. Who should skip it.

What Is Zhi Ju Zi?

Zhi Ju Zi (枳椇子; Zhǐ Jǔ Zǐ; Latin: Hovenia dulcis; English: hovenia fruit) in the current pharmacopoeia is the ripe fruit stalk cluster of Hovenia dulcis, a buckthorn-family tree, gathered around the time of frost and dried, the raw form slightly cool and the stir-fried form milder. It is sweet and sour, and neutral, enters the Stomach and Spleen channels, and its core actions are to resolve alcohol toxin and relieve thirst and vexation, and to clear and drain damp-heat. It usually goes into decoctions or light teas. The usual amount is 6–15 g. It needs no special handling in a decoction and simmers fifteen to twenty minutes with the other pieces.

It is not Ge Hua. Pueraria flower is sweet and cool, and leans toward clearing alcohol heat and awakening the stomach, while Zhi Ju Zi is neutral and also drains damp-heat downward and relieves thirst. A spleen and stomach that are deficiency-cold, with abdominal pain and loose stools, are a poor match. Long heavy use without damp-heat is not advised. Pregnancy and nursing call for caution.

It is used most often for three patterns:

  • After heavy drinking — dizziness, headache, nausea, dry mouth, heat in the chest
  • Damp-heat in the middle and lower jiao — sticky mouth, poor appetite, heavy body, scanty dark urine
  • Mild damp-heat diarrhea or light skin eczema

Sweet, sour, and neutral, it is not a daily “hangover rescue” to keep brewing after every rich meal. When there is no alcohol damage or damp-heat, long use drains the middle and weakens a spleen that was already cold.

When wine and rich diet damage the stomach and damp-heat builds inside, dizziness, nausea, a sticky mouth, and scanty dark urine are common. Zhi Ju Zi is sweet, sour, and neutral. It resolves alcohol toxin, drains damp-heat, and relieves thirst, which is why it appears in Zhi Ju Zi Tang (Hovenia Decoction)–type formulas. It drains more than it builds. A cold weak spleen and stomach, with loose stools and no damp-heat, get worse if more is added.

Zhi Ju Zi is not a catch-all hangover or dampness tea. In a cold weak spleen and stomach, with no alcohol damage or damp-heat, or in pregnancy, using it alone is a poor match. Decoction piece or light tea, and whether it belongs in a formula, should be decided by a licensed Chinese medicine practitioner after pattern diagnosis.

Zhi Ju Zi

Zhi Ju Zi: Materia Medica Profile

Identification & Quality Standard

Hoveniae Semen

Botanical Origin

The dried mature seed of Hovenia dulcis Thunb. (Rhamnaceae).

Production Regions

Primarily produced in the Chinese provinces of Shaanxi, Hubei, Jiangxi, Zhejiang, Jiangsu, Anhui.

Quality Requirements

Superior material is full, reddish-brown and lustrous.

Macroscopic Features

Flat round or oblate, 3~5 mm diameter, about 2 mm thick; externally reddish-brown or brownish-black, smooth, lustrous; ventral surface with a linear hilum; texture hard; after cracking, seed coat thin, cotyledon two, milky white, oily; faint odor; slightly bitter taste.

Main Regions and Quality Identification

Traditional materia medica and industry experience value the producing areas along the Yangtze valley — such as several provinces in central China — but actual quality also depends on variety, harvest time, processing, and storage. In appearance, good-quality Zhi Ju Zi has thick, fleshy fruit stalks, red-brown or yellow-brown, pliable in texture, with a slight fragrance and a sweet taste. The difference between the raw and processed forms: the raw is slightly cool, and its surface is naturally dried and wrinkled; the processed form, after stir-frying, is a little darker in color with a more obvious sweetness, and the cold nature is slightly softened. The common look-alikes are the fruit clusters of other plants of the same genus — their stalks are thinner and less sweet, some with a bitter-astringent taste — note the difference.

Traditional Properties & Historical Lineage

Nature, Flavour & Channel Tropism

Sweet; NeutralStomach

1. Records in Classic Materia Medica

  • Shen Nong Ben Cao Jing: lists Zhi Ju Zi as a top grade in the Wood section — "governs head wind and shaoyin qi."
  • Ming Yi Bie Lu: supplements that it can "stop thirst, remove vexation, and resolve alcohol toxin."
  • Xin Xiu Ben Cao: mentions that it "benefits the stools and urine and removes the heat above the diaphragm."
  • Ben Cao Gang Mu: further states that "its branches and leaves stop hiccup-reversal, resolve alcohol toxin, and dispel insect toxin."
  • De Pei Ben Cao: points out that it "resolves alcohol toxin and treats drunkenness with skin rash."
  • Zhong Hua Ben Cao: summarizes its actions as "resolving alcohol toxin, stopping thirst and removing vexation, clearing damp-heat, and benefiting the stools and urine."

2. How Views of Its Nature Changed

Views among physicians differ. The early physicians mostly stressed its alcohol-toxin-resolving and damp-heat-clearing action, mostly for the discomfort of alcohol-and-food accumulation; some physicians later found it also has a certain spleen-tonifying and stomach-harmonizing effect — usable for the light regulation of spleen-deficiency with dampness retention; some stress that its clearing-draining leans to the lower burner — not for the patterns of pure deficiency without excess — avoiding its misuse for the diarrhea of spleen-stomach deficiency-cold. This makes its scope clearer — not treated as a universal clearing-draining product.

Zhi Ju Zi

Core Efficacies & Traditional Applications

Traditional Functions

Stops thirst and relieves vexation, clears damp-heat, and resolves alcohol toxin.

1. First Direction: Resolving Alcohol Toxin

  • Traditional action: clear the alcohol toxin, stop thirst, and remove vexation.
  • Typical signs: the patterns after drinking too much — such as dizziness and headache after drunkenness, nausea and vomiting, dry mouth, irritability, or the damp-heat accumulation patterns of gastric fullness and short, red urine after drinking.
  • Usual combinations: often paired with Ge Hua, Bai Dou Kou, and Fu Ling — Ge Hua strengthens the alcohol-resolving force, Bai Dou Kou and Fu Ling assist in regulating qi, strengthening the spleen, and draining dampness — avoiding alcohol toxin damaging the spleen and stomach.
  • Who should not self-use: those with spleen-stomach deficiency-cold — usually with abdominal pain and loose stool — should not self-use, or the deficiency-cold symptoms may worsen.

2. Second Direction: Clearing Damp-Heat

  • Traditional action: clear the damp-heat of the spleen-stomach and lower burner.
  • Typical signs: the patterns of improper diet and drink or internal damp-heat accumulation — a sticky mouth, poor appetite, a heavy body, unsmooth urination, or mild skin eczema and short, yellow urine.
  • Usual combinations: often paired with Yi Yi Ren, Zhu Ling, and Chen Pi — Yi Yi Ren and Zhu Ling strengthen the dampness-draining action, Chen Pi regulates the qi and harmonizes the stomach — avoiding over-clearing and draining harming the spleen and stomach.
  • Who should not self-use: those with deficiency-cold diarrhea should not self-use, to avoid damaging the yang qi.

3. Classic Pairing: Zhi Ju Zi With Ge Hua

A common pair is Zhi Ju Zi with Ge Hua: Ge Hua is the usual herb for drinking — good at clearing alcohol toxin and awakening the spleen and stomach; Zhi Ju Zi attends to clearing damp-heat, stopping thirst, and removing vexation at the same time. Combined, Ge Hua leans to the targeted alcohol-resolving, while Zhi Ju Zi assists in easing the damp-heat of alcohol-and-food accumulation — mutually coordinating, strengthening the alcohol-resolving, vexation-removing, dampness-benefiting, and stomach-harmonizing actions. It fits the patterns of dizziness, nausea, a sticky mouth, and short, red urine after drinking too much — but it needs the physician's pattern diagnosis; if the constitution itself is spleen-stomach deficiency-cold, the pairing ratio should be adjusted or yang-warming herbs added.

Zhi Ju Zi

Modern Research

Modern research offers useful context, but Traditional Chinese Medicine prescribes on whole-pattern diagnosis rather than isolated compounds.

1. Main Chemical Constituents

The main constituents detected in the plant are flavonoid compounds, saponins, organic acids, and polysaccharides, plus small amounts of volatile oils and alkaloid constituents. In in vitro experiments, some flavonoid constituents show a certain antioxidant activity; in animal experiments, after giving the Zhi Ju Zi extract to intoxicated mice, the sobering time shortened and the activity of the alcohol-metabolism-related enzymes in the body rose — but this is an animal-experiment result and cannot be directly equated with the human effect. Currently, no sufficient human clinical research reaches a clear efficacy conclusion.

2. Current Research Directions

Current research on Zhi Ju Zi mainly focuses on:

  • The isolation and identification of its active constituents.
  • The evaluation of its in vitro antioxidant activity.
  • The observation of its effect on alcohol metabolism in animal models.

Experiments show that some extracts can assist in regulating metabolism-related physiological indicators in animals, but more human studies are still needed to verify the safety and effectiveness of its actual use.

3. Limitations of Current Research

  • Lab results are not clinical efficacy — the reactions of animal experiments cannot be directly copied to humans.
  • Extracts and monomers are not the same as traditional slices — the dose forms differ completely and cannot be used interchangeably.
  • Varieties, origins, extraction methods, and doses vary between studies — the differences are large, making the experimental results hard to unify.
  • A single component does not define the whole herb — Zhi Ju Zi's overall action is the joint result of many constituents.

Zhi Ju Zi

Comparing Similar Herbs

1. What They Share

Choosing Ge Hua as the similar herb, the two share three main points:

  • Both have the main action of resolving alcohol toxin — common herbs for dealing with drinking too much.
  • Both are used for the traditional patterns of spleen-stomach damp-heat from improper diet and drink — nausea and vomiting, a sticky mouth.
  • Both may appear in hangover-resolving formulas or food-therapy scenes — fitting those with drinking habits for short-term regulation — with the constitution and dose considered in use, avoiding overuse.

2. The Key Differences: Zhi Ju Zi vs. Ge Hua

  • Nature and flavors: Zhi Ju Zi is neutral with sweet and sour flavors — gentle, neither dry-hot nor cold-cool — a neutral clearing-draining product; Ge Hua is cool with a sweet flavor — leaning cool, with a more obvious heat-clearing action — fitting those with heavier damp-heat.
  • Focus: besides resolving alcohol toxin, Zhi Ju Zi also leans to clearing the damp-heat of the spleen-stomach and lower burner — easing the heavy body, unsmooth urination, and thirst after drinking; Ge Hua is more focused on resolving alcohol and awakening the spleen — easing the post-drink nausea, vomiting, dizziness, and headache — with a weaker clearing-draining action than Zhi Ju Zi.
  • Qi tendency: Zhi Ju Zi combines tonifying and purging — it eases the stagnation and harmonizes the spleen and stomach, astringing and dispersing in restraint, without over-dispersing the upright qi; Ge Hua is mainly clearing-purging — cooler, focusing on clearing the excess heat of alcohol toxin — leaning to purging excess.
  • Best fit: Zhi Ju Zi fits the post-drink damp-heat discomfort — a sticky mouth and heavy body — and can also be used for mild damp-heat diarrhea; Ge Hua fits the post-drink excess-heat signs of nausea, vomiting, dizziness, and irritability — with a weaker action on the heavy body.
  • Not suitable: Zhi Ju Zi — neutral; small amounts usually cause no marked discomfort for deficiency-cold, but long-term large use is not advised; Ge Hua — cooler — those with spleen-stomach deficiency-cold, usually with abdominal pain and loose stool, should not use it, or the deficiency-cold symptoms may worsen.
  • Use scenes: Zhi Ju Zi often appears in daily food-therapy regulation — such as tea with other food materials — fitting long-term drinkers with mild damp-heat for daily maintenance; Ge Hua is used more for post-drink emergency regulation, or as the hangover-resolving pairing in formulas — fitting short-term use, not suitable as a long-term daily regulating herb.

3. One-Sentence Summary

Simply put, Zhi Ju Zi leans toward neutral clearing-draining — attending to both hangover relief and regulating the spleen-stomach damp-heat, whereas Ge Hua leans toward cool-natured hangover relief — easing the post-drink excess-heat discomfort. Both can be used for the regulation of drinking too much, but they are not interchangeable.

Zhi Ju Zi

Classical Formulas Containing Zhi Ju Zi

Classic Formula 1: Zhi Ju Zi Tang (Hovenia Decoction)

Combination logic: In Zhi Ju Zi Tang, Zhi Ju Zi is the lord, directly exerting the core actions of resolving alcohol toxin and clearing damp-heat; Ge Gen is the minister, assisting Zhi Ju Zi in strengthening the hangover-resolving and fluid-raising, thirst-stopping actions; Fu Ling is the assistant, strengthening the spleen and draining dampness, helping ease the spleen-stomach discomfort of alcohol-and-food accumulation. This formula mainly solves the problems after drinking too much — alcohol toxin damaging the spleen and stomach and damp-heat arising within — shown as dizziness, nausea, dry mouth, and short, red urine. Zhi Ju Zi alone cannot be used, because a single herb's action is single and cannot attend to the auxiliary regulation needs of regulating qi and strengthening the spleen.

Traditional use: traditionally for the patterns of alcohol-toxin accumulation within and spleen-stomach damp-heat from drinking too much — a common hangover-resolving formula of ancient times.

Modern note: modern clinical use requires the doctor's pattern diagnosis and standard care — do not self-apply just because the formula name relates to hangover relief; if marked discomfort appears after drinking, seek medical care promptly.

Classic Formula 2: Guai Zao San (Hovenia Powder)

Combination logic: The main ingredient of Guai Zao San is Zhi Ju Zi, paired with Bai Kou Ren and Chen Pi. Zhi Ju Zi is the lord — resolving alcohol toxin and clearing damp-heat; Bai Kou Ren is the minister — regulating qi and harmonizing the stomach, easing the post-drink nausea and vomiting; Chen Pi is the assistant — strengthening the spleen and drying dampness, regulating the spleen-stomach transport. This formula mainly solves the mild spleen-stomach damp-heat patterns of improper diet and drink — shown as gastric fullness and distension, poor appetite, and a sticky mouth.

Traditional use: traditionally for the mild patterns of spleen-stomach damp-heat caused by improper diet and drink.

Modern note: modern clinical use requires the doctor's pattern diagnosis — if severe nausea, vomiting, or abdominal pain appears, do not self-use this formula — seek medical care promptly.

Formulas vs. Single Herbs

A formula is the joint result of many herbs — different herbs combine with one another to attend to different symptoms, with a more complete action; a single herb cannot simply replicate a full formula's effect, because a single herb's action is single and cannot attend to the auxiliary regulation needs of regulating qi and strengthening the spleen. The doses and combinations in a formula are holistic — each herb's amount and pairing are determined by the pattern-differentiation result and cannot be casually adjusted. Do not build formulas from online articles — readers easily ignore pattern differentiation and dose, leading to improper use. A herb that works in a formula does not mean taking it alone produces the same effect — a whole formula's action is the synergy of many herbs, and a single herb cannot reach the same regulating effect.

Diet & Daily Home Use

1. Home Tea

Tea — Zhi Ju Zi Hangover Tea: dried Zhi Ju Zi 10 g, Chao Mai Ya 6 g, Chen Pi 3 g. Quickly rinse all the materials with clean water, put them into a teapot, add boiling water, steep 10 minutes, and drink; it can be re-steeped until the taste fades. Suited to those whose daily diet leans rich and who have light drinking habits — with a sticky mouth, poor appetite, and a heavy body — as a daily regulating tea, 2–3 times a week. Not for those with spleen-stomach deficiency-cold — usually with abdominal pain and loose stool — or pregnant women. Note: Zhi Ju Zi is a medicinal slice and cannot be directly eaten in large amounts as an ordinary food; buy the processed slices from a regular pharmacy.

2. Decoction and Processing Differences

The raw Zhi Ju Zi is slightly cool with a stronger clearing-draining action — fitting the heavier damp-heat cases; the stir-fried Zhi Ju Zi is slightly softened in nature with a more obvious sweetness and reduced cold — fitting daily regulation better. For home decoction, Zhi Ju Zi needs no pre-boiling, late addition, or bag-boiling — it can be decocted together with the other food or herbs, with the decoction time controlled at 15–20 minutes. Different forms cannot be converted directly — the doses of the slices, extracts, and capsules differ greatly — do not convert the slice dose directly into the dose of another form.

3. Dosage and Course

The common dose of Zhi Ju Zi in traditional prescriptions is 6–15 g; the food-therapy dose is usually 3–10 g — smaller than the medicinal dose. Long-term continuous use is not advised — generally use it as a short-term regulation, with continuous use not exceeding 2 weeks; stop once the symptoms ease, and consult a physician if they do not improve. Special groups — such as pregnant women, children, and the elderly — need the physician's or pharmacist's advice before use, with the dose or pairing adjusted.

Zhi Ju Zi

Contraindications & Safety Warnings

1. Who Should Avoid It

  • Spleen-stomach deficiency-cold — usually with abdominal pain, loose stool, and fear of cold — should not self-use Zhi Ju Zi, because its clearing-draining action may worsen the deficiency-cold symptoms.
  • Pregnancy and breastfeeding — special body state — consult a physician before use, to avoid affecting oneself or the health of the fetus or infant.
  • Children and the elderly — weaker body function — use with caution, under a physician's guidance.
  • Liver or kidney impairment — weaker metabolism — consult a physician before use, to avoid adding burden to the liver and kidneys.
  • Allergy to Zhi Ju Zi or Rhamnaceae plants — not suitable for use.
  • Those in special treatment — such as anticoagulation or glucose-lowering treatment — consult a physician before use, to avoid drug interactions.

2. Interactions and Diet Notes

Zhi Ju Zi currently has no clear reports of serious interactions with other drugs, but those taking anticoagulants, blood-pressure medications, glucose-lowering medications, or sedatives should consult a physician before use, because individual differences may have potential effects. There is no sufficient evidence of a general "food clash" between ordinary foods, but certain herbs can interact with specific drugs — those on medication should consult a doctor or pharmacist first, and do not pair herbs on your own.

3. Adverse Reactions and Overdose Risk

Zhi Ju Zi is generally safe at normal doses; a few people may have mild gastrointestinal discomfort — such as a dull stomach ache and increased stool frequency. Overuse may add burden to the spleen and stomach — with nausea, vomiting, and abdominal pain. If marked discomfort, allergy signs, persistent vomiting, breathing difficulty, altered consciousness, or rapidly worsening symptoms appear, stop at once and seek medical care — do not delay the illness.

Frequently Asked Questions About Zhi Ju Zi

What is Zhijuzi? Is it the same as Gehua or Zhishi?
Zhijuzi is the dried mature seed of Hovenia dulcis, Hovenia acerba or Hovenia trichocarpa, Latin name Hoveniae Semen. It is a common Chinese medicine centered on resolving alcohol toxin, quenching thirst and eliminating vexation, stopping vomiting, and promoting urination and defecation. Gehua resolves alcohol and awakens the spleen. Zhishi breaks qi and reduces accumulation. They cannot be used interchangeably in equal amounts. Prescribe as Zhijuzi. Caution in spleen-stomach deficiency cold.
What are the composition and effects of Zhijuzi?
Pharmacopoeial name Zhijuzi, Latin Hovenia dulcis Thunb. etc. Sweet in taste, neutral in nature, enters the Heart, Spleen and Lung meridians. Functions to resolve alcohol toxin, quench thirst and eliminate vexation, stop vomiting, and promote urination and defecation. Used for drunkenness, vexing thirst, vomiting, and inhibited urination and defecation. Resolves alcohol and quenches thirst.
How to choose between raw and processed? Can Gehua replace it?
Seeds are used raw. Gehua emphasizes alcohol toxin rather than strongly promoting urination, and cannot replace it in equal amounts. Commercial products are standardized; do not adjust arbitrarily.
What is the dosage of Zhijuzi? Can it be used daily as an alcohol-resolving tea?
Decoction, 6-15g. Modern use requires physician-determined dosage. It is not a year-round "Zhijuzi tea." Spleen-stomach deficiency cold will be further injured by prolonged use. Drunkenness requires short-term, physician-determined dosage and cannot replace evaluation.
What are the contraindications of Zhijuzi? Can pregnant women use it?
Not suitable for spleen-stomach deficiency cold. Pregnant women require physician evaluation. Stop if loose stools or abdominal pain occur. Seek immediate medical care for severe vomiting or high fever.
Can Zhijuzi resolve alcohol, quench thirst, and stop vomiting?
It can assist drunkenness, vexing thirst, vomiting, and inhibited urination and defecation. It resolves alcohol toxin, quenches thirst and eliminates vexation, stops vomiting, and promotes urination and defecation, but is not a specific remedy for all drunkenness or all vomiting.
Can Zhijuzi be taken daily as an alcohol-resolving or thirst-quenching tea?
Drunkenness can be used short-term in formulas; spleen-stomach deficiency cold will be further injured. The idea that "Zhijuzi must resolve alcohol" cannot replace evaluation. Resolving alcohol and quenching thirst requires physician-determined formulation and dosage.
How to choose between Zhijuzi, Gehua, Zhishi, Chenpi, and Fuling?
Zhijuzi resolves alcohol and quenches thirst, suited to drunkenness. Gehua resolves alcohol and awakens the spleen. Zhishi breaks qi and reduces accumulation. Chenpi regulates qi and transforms phlegm. Fuling promotes urination and drains dampness. Choose Zhijuzi for resolving alcohol; Gehua for awakening the spleen; Zhishi for regulating qi; Chenpi for transforming phlegm; Fuling for promoting urination. Pattern differentiation applies, but large doses of Zhijuzi are contraindicated in spleen-stomach deficiency cold.
How is Zhijuzi commonly modified? What is a representative usage?
Modifications depend on the pattern. Add Gehua for drunkenness; add Maidong for vexing thirst. Specify Zhijuzi; do not substitute Gehua in equal amounts for quenching thirst.
How to select and store Zhijuzi?
Choose regular Chinese medicinal materials with intact seeds. Discard if moldy, damp, or abnormal in odor. Store in a dry place. Purchase "Zhijuzi"; do not substitute Gehua or Zhishi in equal amounts for resolving alcohol, quenching thirst, and stopping vomiting.

Medical Disclaimer — This article is provided for educational purposes only and describes traditional Chinese medicine concepts. It is not medical advice, and it is not intended to diagnose, treat, cure or prevent any disease. Always consult a qualified practitioner before using any herb, particularly if you are pregnant, nursing, taking medication or managing a diagnosed condition.

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Zhi Ju Zi (Raisin Tree Seed): Relieves thirst and vexation, clears damp-heat, and resolves alcohol toxicity