Roots and rhizomesHemostaticBoehmeriae Radix et Rhizoma

Zhu Ma Gen (Ramie Root)

A practical guide to Zhu Ma Gen: what it is, how Traditional Chinese Medicine uses it, the classical formulas it appears in, and who should be careful with it.

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Last reviewed Oct 28, 2026

Quick Facts

Latin NameBoehmeriae Radix et Rhizoma
Chinese Name & Pinyin 苧麻根 · Zhu Ma Gen
Medicinal PartRoots and rhizomes
The itemZhu Ma Gen is the dried root of the ramie plant. Huang Qin (skullcap) and other roots are not this drug.
Nature and channelsCold, sweet. Enters the Heart, Liver, Kidney, and Bladder. Cold sweet cools the blood, stops bleeding, clears heat, and settles the fetus.
Pharmacopoeia lineCools the blood and stops bleeding; clears heat and settles the fetus. Used for heat-type bleeding and heat-type unsettled pregnancy.
Pattern cuesNosebleed. Bleeding gums. Blood in stools or urine. Heavy bright period. Restless fetus. Irritability with dry mouth.
In this articleZhu Ma Gen versus Huang Qin. Cooling blood and holding the fetus versus broadly clearing heat. Why cold-pattern bleeding should skip it. Home tea.

What Is Zhu Ma Gen?

Zhu Ma Gen (苎麻根; Zhù Má Gēn; Latin: Boehmeriae Radix; English: ramie root) is the dried root of the ramie plant — the tall herb whose silver-backed leaves and tough stem fibers once wove cloth, and whose root has been used for a thousand years for heat-type bleeding and unsettled pregnancy. It is cold and sweet, enters the Heart, Liver, Kidney, and Bladder channels, and its core actions are to cool the blood and stop bleeding, and to clear heat and settle the fetus. It is the gentle, astringent herb for heat-driven bleeding. The usual amount is 10–15 g in a decoction. It does not need first, last, or wrapped decoction handling.

It is not Huang Qin. Skullcap is cold and bitter, and it clears heat and dries dampness more directly, with a wide heat-clearing reach; this root is cold and sweet, moist and astringent, and its bleeding-stopping and fetus-settling sides are clearer. In bleeding from a cold weak spleen-stomach — pale thin blood, cold belly, loose stools — or without the heat pattern, using it on your own is a poor match. Bleeding that will not stop, or a pregnancy that will not settle, needs a clinic first. Do not take it yourself for a long time.

It is used most often for three patterns:

  • Nosebleed, bleeding gums, blood in stools or urine, a heavy bright-red period — heat pushing the blood out of its vessels
  • Pregnancy with a restless fetus, irritability, dry mouth, scanty dark urine, light spotting — fetal heat
  • Pale thin bleeding with cold belly and loose stools — skip it

Cold and sweet, it is not a daily "bleeding-stopper tea" to keep drinking. Cooling and astringing when there is no heat, or in a cold weak spleen-stomach, chills the middle instead of helping.

When heat pushes the blood out of its vessels — from heat in the blood or heat gathering in the womb — nosebleeds, gum bleeding, blood in stools or urine, or a heavy bright period follow; when fetal heat stirs, the pregnancy feels restless with irritability and dry mouth. Zhu Ma Gen is cold and sweet. It cools the blood and holds the fetus, which is why it appears in Zhu Gen Tang (Ramie Root Decoction)–type formulas. It holds more than it scatters. In cold-pattern bleeding, or without heat, more makes it worse.

Zhu Ma Gen is not a catch-all bleeding or pregnancy herb. In cold-pattern bleeding, without heat, or in a cold weak spleen-stomach, using it alone is a poor match. Whether it belongs in a formula, and at what dose, should be decided by a licensed Chinese medicine practitioner after pattern diagnosis.

Zhu Ma Gen

Zhu Ma Gen: Materia Medica Profile

Identification & Quality Standard

Boehmeriae Radix et Rhizoma

Botanical Origin

The dried root and rhizome of Boehmeria nivea (L.) Gaudich. (Urticaceae).

Production Regions

Primarily produced in Jiangsu, Shandong, Shanxi.

Quality Requirements

Superior is thick, solid, brown.

Macroscopic Features

Root irregular cylindrical, bent, 4~30cm long, 0.4~4.5cm diameter. Externally grayish-brown, with wrinkled bark and warty root scars. Hard, broken surface brownish.

Main Regions and Quality Identification

Classic texts and trade experience favor roots from several southern provinces, but quality still depends on species, harvest time, processing, and storage. Different regions differ slightly in root thickness and fiber content. Good sheng Zhu Ma Gen is cylindrical, slightly curved, gray-brown on the surface with longitudinal wrinkles and root scars, a brown bark section on the cut with a wide wood core, and a tough resilient feel; the processed form is faintly yellow with light scorch spots. The common look-alikes are other herb roots — the genuine ramie root is strongly fibrous with radiating lines on the break; look-alikes have less fiber and break more easily.

Traditional Properties & Historical Lineage

Nature, Flavour & Channel Tropism

Sweet; ColdHeartLiver

1. Records in Classic Materia Medica

  • Ming Yi Bie Lu: notes it "settles the fetus and relieves vexation."
  • Xin Xiu Ben Cao: adds it "is used for epidemic heat illness, great thirst, headache, breaking blood, and stopping frequent urination."
  • Ben Cao Gang Mu: records it "is used for abscesses, erysipelas-type rashes, and insect or snake injuries."

All the records circle the bleeding-stopping, fetus-settling, and heat-clearing work.

2. How Views of Its Nature Changed

Some doctors leaned on the fetus-settling side — a pregnancy-care herb; others stressed the clear-and-hold bleeding side — for heat-type bleeding; still others drew the line — a cold weak spleen-stomach should not use it long. The range stayed clear, and the herb was never used as a universal catch-all.

Zhu Ma Gen

Core Efficacies & Traditional Applications

Traditional Functions

Cools blood and stops bleeding, calms the fetus, clears heat and resolves toxin.

1. Main Use 1: Cooling the Blood and Stopping Bleeding

(1) Traditional action: stopping heat-driven bleeding by cooling the blood. (2) Typical patterns: nosebleed, bleeding gums, blood in stools or urine, or a heavy bright-red sticky period — with dry mouth, irritability, and scanty dark urine. (3) Usual pairings: Sheng Di Huang (raw rehmannia) to strengthen the cooling; Pu Huang (cattail pollen) for the stopping; by site — Di Yu (sanguisorba) for blood in stools, Xiao Ji (field thistle) for blood in urine. (4) Not for self-use: spleen-stomach-cold bleeding — pale thin blood, cold belly, loose stools; or pregnancy without an unsettled or heat pattern.

2. Main Use 2: Clearing Heat and Settling the Fetus

(1) Traditional action: easing heat-type unsettled pregnancy. (2) Typical patterns: pregnancy with irritability, dry mouth, yellow urine, a restless fetus, a dragging lower belly, or light bright-red spotting — heat gathering in the womb with disharmonized qi and blood. (3) Usual pairings: Huang Qin (skullcap) to clear the heat and Bai Zhu (atractylodes) to fortify the spleen and hold the fetus — together they clear fetal heat and steady the pregnancy. (4) Not for self-use: spleen-stomach-cold unsettled pregnancy — cold lower belly, warmth-seeking, loose stools; or pregnancy with lower-back ache and dragging without heat.

3. A Classic Pairing

Zhu Ma Gen pairs classically with Huang Qin: the skullcap clears heat and drains fire — clearing fetal heat; the ramie root cools blood, stops bleeding, and settles the fetus — calming the heat-driven agitation and light bleeding. Together they clear the heat in the womb and steady the pregnancy. This pair belongs to a practitioner's pattern diagnosis for the specific pregnant constitution — never self-pairing.

Zhu Ma Gen

Modern Research

Modern research offers useful context, but Traditional Chinese Medicine prescribes on whole-pattern diagnosis rather than isolated compounds.

1. Main Chemical Constituents

Detected in the root are flavonoids (rutin, quercetin), alkaloids, coumarins, polysaccharides, and volatile oil. In vitro, some flavonoids show antioxidant activity; in animals, extracts shorten bleeding time and show some regulating effect on uterine smooth muscle. No sufficient human clinical conclusion exists yet.

2. Current Research Directions

Current work centers on the bleeding-stopping activity, uterine regulation, and heat-clearing directions. Some components show a mild anti-inflammatory tendency in vitro — whether any of this carries over to people still needs human research.

3. Limitations of Current Research

  • Lab results are not clinical efficacy — dish and animal settings differ from the human body.
  • Extracts are not decoction pieces — component ratios and doses differ completely from the daily root pieces.
  • Doses and preparations vary between studies — some use concentrated extracts, some regular-dose pieces; results cannot be merged.
  • One component does not define the whole herb — the root acts as a team of constituents.

Zhu Ma Gen

Comparing Similar Herbs

1. What They Share

  • Both clear heat.
  • Both are used for heat-type patterns and appear in pregnancy-care formulas and food remedies.
  • Both need constitution and dose care — no casual use.

2. Key Differences

Nature and flavor: Zhu Ma Gen is cold and sweet — moist, astringent, and gentle; Huang Qin is cold and bitter — bitter-cold and drying, with a more direct heat-clearing and damp-drying edge. Focus: Zhu Ma Gen cools blood, stops bleeding, and settles the fetus — the bleeding-stopping side is clearer, fit for heat-type bleeding; Huang Qin clears heat, drains fire, dries dampness, and settles the fetus — a wider heat-clearing reach, including damp-heat. Tendency: Zhu Ma Gen holds and descends — astringing the bleeding, calming the fetal agitation; Huang Qin drains and dries — clearing heat pathogens with a draining, drying edge. Best fit: Zhu Ma Gen for heat-type bleeding and unsettled pregnancy with irritability and dry mouth; Huang Qin for damp-heat — chest tightness with a bitter mouth, or fetal heat with a thick greasy tongue coat. Who should avoid: Zhu Ma Gen is wrong for cold-pattern bleeding and unsettled pregnancy; Huang Qin is wrong for a cold weak spleen-stomach, loose stools, and deficiency patterns without heat. Where you meet them: Zhu Ma Gen as a supporting herb for pregnancy spotting or daily heat-type care; Huang Qin where the heat is marked — damp-heat jaundice, lung-heat cough, or clearly hot pregnancies.

3. One-Line Takeaway

In short, Zhu Ma Gen moistly cools the blood and gently settles the fetus; Huang Qin bitterly clears heat and dries dampness. Both can appear in heat-type pregnancy care — but they are not stand-ins for each other.

Zhu Ma Gen

Classical Formulas Containing Zhu Ma Gen

Classic Formula 1: Zhu Gen Tang

Role of this herb: in Zhu Gen Tang (Ramie Root Decoction), Zhu Ma Gen is the monarch — cooling the blood, stopping bleeding, and settling the fetus — with Dang Gui (angelica) and Bai Shao (white peony) nourishing the blood and harmonizing it. The root does the core work while the blood-nourishing herbs repair the loss; alone, the root cannot replenish the blood the bleeding cost. Traditional focus: heat-type unsettled pregnancy — light bright-red spotting, irritability, dry mouth. Modern note: professional diagnosis first — never self-apply by name; pregnancy care is practitioner-managed.

Classic Formula 2: Zhu Ma Gen San

Role of this herb: in Zhu Ma Gen San (Ramie Root Powder), Zhu Ma Gen is the monarch — cooling blood and stopping bleeding — with Pu Huang and Xiao Ji strengthening the stopping, plus heat-clearing, urine-easing partners. The target is heat-driven blood in urine or stools and heavy periods. Alone, one root's stopping is limited; the team covers bleeding from different sites. Traditional focus: heat pushing the blood out — blood in urine or stools, heavy periods. Modern note: professional diagnosis first — the site and pattern decide the formula.

Formula vs. Single Herb

A formula is a coordinated team; a single herb cannot copy a full formula's effect. The doses and pairings are designed as a whole — a herb that works in a formula does not automatically work the same way alone. Do not self-formulate from web articles, and never use a single herb to stand in for a prescribed formula.

Diet & Daily Home Use

1. Home Tea

Example — Zhu Ma Gen wax gourd tea: Zhu Ma Gen 10 g (medicinal pieces), wax gourd peel 15 g, a little rock sugar — rinse the root, decoct with the peel 20 minutes, strain, sweeten lightly. Fit: summer or damp-heat constitution daily care — scanty yellow urine, dry mouth. Not for: a cold weak spleen-stomach, loose stools. Frequency: 1–2 times a week, not long-term. Zhu Ma Gen is a medicinal piece, not ordinary food — if you buy ordinary ramie rather than medicinal pieces, confirm the source is safe.

2. Decoction and Processing Differences

The raw root leans to clearing heat, cooling blood, and stopping bleeding — for heat-type bleeding; the stir-fried form leans to gentler pregnancy care. At home, decoct the raw root with the other herbs — no special handling; soaking 30 minutes first helps release the material. Different forms cannot be converted directly — medicinal pieces are not retail tea bags.

3. Dosage and How Long to Use

The classic range is 10–15 g under professional direction; food-use amounts are 5–10 g. Not for long continuous use — a course of no more than 2 weeks; if nothing settles, ask a practitioner to adjust. Pregnancy and nursing use only after consulting a practitioner or pharmacist — no self-deciding on dose or course.

Zhu Ma Gen

Contraindications & Safety Warnings

1. Who Should Avoid It

A cold weak spleen-stomach — frequent belly pain, loose stools, cold hands and feet; pregnancy without unsettled-fetus or heat patterns — no self-use without the pattern; nursing mothers with a cold weak spleen-stomach — be cautious; children and people with liver or kidney impairment — professional evaluation first; allergy to nettle-family plants — avoid.

2. Interactions and Diet Notes

No firm evidence shows Zhu Ma Gen affects anticoagulants, blood-pressure, or blood-sugar medicines, but anyone on medication should consult a doctor or pharmacist first. No blanket "food clash" with ordinary foods is established, but herbs can interact with specific medicines — anyone on medication should check first.

3. Side Effects and Overuse

At normal doses the root is usually safe; a few people get mild stomach upset — nausea, loose stools. Overuse can worsen a cold weak spleen-stomach. Stop and seek care at once for marked discomfort, an allergic reaction such as rash and itching, persistent vomiting, trouble breathing, confusion, or a rapid worsening of symptoms.

Frequently Asked Questions About Zhu Ma Gen

What is Zhumagen? Is it the same as Qiancao or Baimaogen?
Zhumagen is the dried root and rhizome of Boehmeria nivea, Latin name Boehmeriae Radix et Rhizoma. It is a common Chinese medicine centered on cooling the blood and stopping bleeding, calming the fetus, and clearing heat and detoxifying. Qiancao cools the blood and stops bleeding while activating blood. Baimaogen cools the blood and stops bleeding while promoting urination. They cannot be used interchangeably in equal amounts. Prescribe as Zhumagen. Caution in spleen-stomach deficiency cold.
What are the composition and effects of Zhumagen?
Pharmacopoeial name Zhumagen, Latin Boehmeria nivea (L.) Gaud. Sweet in taste, cold in nature, enters the Heart and Liver meridians. Functions to cool the blood and stop bleeding, calm the fetus, and clear heat and detoxify. Used for fetal restlessness, threatened miscarriage, hematuria, and external bleeding; externally for the initial stage of abscesses and swelling. Cools the blood and calms the fetus.
How to choose between raw and processed? Can Qiancao replace it?
Root and rhizome are used raw. Qiancao emphasizes activating blood rather than strongly calming the fetus, and cannot replace it in equal amounts. Commercial products are standardized; do not adjust arbitrarily.
What is the dosage of Zhumagen? Can it be used daily as a bleeding-stopping tea?
Decoction, 10-30g. Modern use requires physician-determined dosage. It is not a year-round "Zhumagen tea." Spleen-stomach deficiency cold will be further injured by prolonged use. Fetal restlessness requires short-term, physician-determined dosage and cannot replace evaluation.
What are the contraindications of Zhumagen? Can pregnant women use it?
Not suitable for spleen-stomach deficiency cold. Pregnant women require physician evaluation. Stop if loose stools or abdominal pain occur. Seek immediate medical care for severe bleeding or high fever.
Can Zhumagen cool the blood, stop bleeding, and calm the fetus?
It can assist fetal restlessness, threatened miscarriage, hematuria, and external bleeding; externally for the initial stage of abscesses and swelling. It cools the blood and stops bleeding, calms the fetus, and clears heat and detoxifies, but is not a specific remedy for all bleeding or all fetal restlessness.
Can Zhumagen be taken daily as a bleeding-stopping or fetus-calming tea?
Blood heat bleeding can be used short-term in formulas; spleen-stomach deficiency cold will be further injured. The idea that "Zhumagen must stop bleeding" cannot replace evaluation. Cooling the blood and calming the fetus requires physician-determined formulation and dosage.
How to choose between Zhumagen, Qiancao, Baimaogen, Cebaiye, and Aiye?
Zhumagen cools the blood and calms the fetus, suited to fetal restlessness. Qiancao cools the blood and activates blood. Baimaogen cools the blood and promotes urination. Cebaiye cools the blood and stops bleeding. Aiye warms the channels and stops bleeding while calming the fetus. Choose Zhumagen for stopping bleeding; Qiancao for activating blood; Baimaogen for promoting urination; Cebaiye for cooling the blood; Aiye for warming the channels. Pattern differentiation applies, but large doses of Zhumagen are contraindicated in spleen-stomach deficiency cold.
How is Zhumagen commonly modified? What is a representative usage?
Modifications depend on the pattern. Add Aiye for fetal restlessness; add Cebaiye for bleeding. Specify Zhumagen; do not substitute Qiancao in equal amounts for calming the fetus.
How to select and store Zhumagen?
Choose regular Chinese medicinal materials with intact roots and rhizomes. Discard if moldy, damp, or abnormal in odor. Store in a dry place. Purchase "Zhumagen"; do not substitute Qiancao or Baimaogen in equal amounts for cooling the blood, stopping bleeding, and calming the fetus.

Medical Disclaimer — This article is provided for educational purposes only and describes traditional Chinese medicine concepts. It is not medical advice, and it is not intended to diagnose, treat, cure or prevent any disease. Always consult a qualified practitioner before using any herb, particularly if you are pregnant, nursing, taking medication or managing a diagnosed condition.

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Zhu Ma Gen (Ramie Root): Cools blood, stops bleeding, calms the fetus, and clears heat-toxin