Whole herbsBlood-activatingAchyranthis Asperae Herba

Dao Kou Cao (Rough Achyranthes Herb)

A practical guide to Dao Kou Cao: what it is, how Traditional Chinese Medicine uses it, the classical formulas it appears in, and who should be careful with it.

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Last reviewed Oct 29, 2026

Quick Facts

Latin NameAchyranthis Asperae Herba
Chinese Name & Pinyin 倒扣草 · Dao Kou Cao
Medicinal PartWhole herbs
The itemDao Kou Cao is the dried whole herb of Achyranthes aspera, usually used raw. Tu Niu Xi is not this herb. It usually goes into decoctions.
Nature and channelsBitter, sour, cold. Enters the Liver and Bladder. It clears and drains damp-heat, and activates blood to disperse stasis.
Pharmacopoeia lineClears and drains damp-heat. Activates blood and disperses stasis. Used for scanty dark urine, heavy swollen lower limbs, damp-heat jaundice, falls with bruising swelling, and delayed clotted periods.
Pattern cuesScanty dark urine. Heavy swollen lower limbs. Damp-heat jaundice. Bruising after a fall. Clotted periods.
In this articleDao Kou Cao versus Tu Niu Xi. Damp-heat draining versus collateral unblocking. Why long-term daily use is not advised. Why pregnancy and heavy menses should skip it. Who should not self-use it.

What Is Dao Kou Cao?

Dao Kou Cao (倒扣草; Dào Kòu Cǎo; Latin: Achyranthes aspera; English: devil's horsewhip) in the current pharmacopoeia is the dried whole herb of Achyranthes aspera, a perennial of the amaranth family, gathered around the summer flowering period, usually used raw. It is bitter, sour, and cold, enters the Liver and Bladder channels, and its core actions are to clear and drain damp-heat, and to activate blood and disperse stasis. It usually goes into decoctions. The usual amount is 10–15 g. It needs no special handling in a decoction. In a light home tea, a small amount of 3–6 g is used briefly.

It is not Tu Niu Xi. Tu Niu Xi is milder, leans sweet and bland, and more clearly unblocks the collaterals for joint pain and numbness after a fall. Dao Kou Cao is colder and stronger at draining lower-jiao damp-heat. A deficiency-cold constitution is a poor match. Pregnancy is a caution. Heavy menses and bleeding disorders should not use it on their own.

It is used most often for three patterns:

  • Damp-heat pouring downward: scanty dark urine, heavy swollen lower limbs, beriberi swelling pain
  • Damp-heat jaundice: yellowing skin, abdominal fullness
  • Blood stasis after a fall, delayed dark clotted periods

Bitter, sour, and cold, it is not a daily “lower-jiao clearing” herb to keep increasing. Draining when there is no damp-heat, or moving blood during heavy menses, brings discomfort or bleeding.

When damp-heat accumulates in the lower jiao, or blood stasis blocks the channels, scanty dark urine, swollen limbs, bruised swelling, and clotted periods are common. Dao Kou Cao is bitter, sour, and cold. It drains damp-heat and moves blood, which is why it appears in Dao Kou Cao Tang (Devil's-Horsewhip Decoction)–type formulas. It drains and moves more than it holds. A cold weak stomach, with no damp-heat, gets worse if more is added.

Dao Kou Cao is not a catch-all water or blood-moving herb. In deficiency-cold, in pregnancy, or with bleeding tendencies, using it alone is a poor match. Raw or stir-fried, and whether it belongs in a formula, should be decided by a licensed Chinese medicine practitioner after pattern diagnosis.

Dao Kou Cao

Dao Kou Cao: Materia Medica Profile

Identification & Quality Standard

Achyranthis Asperae Herba

Botanical Origin

The dried whole herb of Achyranthes aspera L. (Amaranthaceae).

Production Regions

Primarily produced in the Chinese provinces of Guangdong, Guangxi, Yunnan, Guizhou, Fujian, Jiangxi.

Quality Requirements

Superior material is dry, leafy, with flower spikes.

Macroscopic Features

Whole herb 30~100 cm long; root cylindrical, curved, surface yellowish-brown; stem opposite-branched, quadrangular, green or purple, with sparse soft hairs; leaves opposite, elliptical or obovate; spikes terminal, reflexed after flowering (hence inverted), bracts spiny; texture brittle; faint odor; slightly bitter taste.

Main Regions and Quality Identification

Traditional materia medica and industry experience value the Dao Kou Cao of certain southern producing regions, but actual quality also depends on variety, harvest time, processing, and storage. The main producing areas are spread across several provinces in southern China; plants from different areas differ slightly in form — the plants from humid southern regions have broader leaves and stouter stems. For quality: good raw Dao Kou Cao should be dry, with an upright stem, obvious nodes, intact leaves, and a grayish-green color; it tastes slightly bitter, and is light, brittle, and easily broken. The processed form is mostly cut segments stir-fried to a slight yellow, with a fainter odor. The common look-alikes are other Niu Xi-type plants of the same genus — such as Hong Niu Xi, whose stem color leans red and whose medicinal form differs from Dao Kou Cao; watch the difference.

Traditional Properties & Historical Lineage

Nature, Flavour & Channel Tropism

Sweet, Bitter; CoolLiverLungBladder

1. Records in Classic Materia Medica

  • Ming Yi Bie Lu: mentions that the Niu Xi-type herbs can "treat flaccidity and paralysis, and expel qi and blood"; Dao Kou Cao, as a regional substitute of Niu Xi, is included in such records.
  • Ben Cao Gang Mu: records that it can "treat malaria and promote urination" — corresponding to its clear-drain damp-heat action.
  • De Pei Ben Cao: clearly states that "the bitter can drain heat, the sour can disperse stasis, and it enters the liver and bladder channels" — further defining its channel entry and nature.
  • Zhong Hua Ben Cao: organizes the folk application experience, supplementing the records of its use for damp-heat jaundice and falls and injuries.

2. How Views of Its Nature Changed

Views among physicians differ somewhat. Some ancient physicians leaned more to its blood-activating, stasis-dispersing action, using it for falls and injuries and amenorrhea with abdominal pain; some stressed its clear-drain damp-heat action, mostly for the difficult urination and beriberi swelling pain of damp-heat pouring downward; some suggested its scope is limited and it is not for those of a deficiency-cold constitution, to avoid worsening the cold signs. This difference also shows that Dao Kou Cao's functions are relatively concentrated — not a universal medicine; the different emphases are supplements based on clinical experience, not a complete denial of its nature.

Dao Kou Cao

Core Efficacies & Traditional Applications

Traditional Functions

Activates blood and dispels stasis, promotes diuresis and relieves stranguria, releases exterior and clears heat.

1. First Direction: Clearing and Draining Damp-Heat

  • Traditional action: clear the pathological products produced by damp-heat accumulation inside the body, easing the discomfort caused by damp-heat.
  • Typical signs: traditionally used for the scanty dark urine and lower-limb swelling of damp-heat pouring downward, as well as damp-heat jaundice and beriberi swelling pain — often shown as dark-yellow urine, difficult urination, heavy, swollen lower limbs, and yellowing skin.
  • Usual combinations: clinically often paired with Che Qian Zi and Ze Xie to strengthen the clear-drain urination action, or with Yin Chen and Zhi Zi to strengthen the clear-drain damp-heat and jaundice-resolving effect.
  • Who should not self-use: those of a deficiency-cold constitution — people who usually fear cold, have cold hands and feet, and loose stool — should not self-use, to avoid worsening the deficiency-cold; pregnant women are also advised not to self-use.

2. Second Direction: Activating Blood and Dispersing Stasis

  • Traditional action: free the blocked qi and blood inside the body and disperse local blood-stasis blockage.
  • Typical signs: traditionally used for the local swelling and pain of falls and injuries, and for the stasis-blocked patterns of amenorrhea and dysmenorrhea in women — often shown as local bruising, swelling, and pain, delayed periods, and dark periods with clots.
  • Usual combinations: clinically often paired with Hong Hua and Tao Ren to strengthen the blood-activating, stasis-dispersing action, or with Ru Xiang and Mo Yao to ease the swelling and pain of falls and injuries.
  • Who should not self-use: women with heavy menstrual flow should not self-use during their period, to avoid increasing the flow; those with bleeding disorders also need caution, to avoid worsening the bleeding tendency.

3. Classic Pairing: Dao Kou Cao With Che Qian Zi

The common pair is Dao Kou Cao with Che Qian Zi. Che Qian Zi can clear heat, promote urination, percolate dampness, and stop diarrhea; Dao Kou Cao can clear and drain damp-heat and activate blood to disperse stasis. Combined, the two strengthen the clear-drain damp-heat and free-urination action, while avoiding the cold-damaging-stomach problem that a purely clear-drain herb may bring — mutually coordinating — fitting the difficult urination and lower-limb swelling of damp-heat pouring downward. Note: all pairings need the physician's pattern diagnosis — adjust the dose and combination to your constitution and pattern; do not combine on your own.

Dao Kou Cao

Modern Research

Modern research offers useful context, but Traditional Chinese Medicine prescribes on whole-pattern diagnosis rather than isolated compounds.

1. Main Chemical Constituents

Research shows that the constituents detected in Dao Kou Cao mainly include saponins, flavonoids, alkaloids, and polysaccharides. Among them, the saponins are the main active constituents detected in the plant. In in vitro experiments, these constituents show a certain anti-inflammatory activity; in animal experiments, mice given the Dao Kou Cao extract show a certain degree of lowered inflammatory markers. Currently, no sufficient human clinical research has reached a clear conclusion about the action of these constituents — the research is still at the stage of experimental observation.

2. Current Research Directions

Current research mainly focuses on the anti-inflammatory and diuretic actions of Dao Kou Cao. In experiments, its extract can, to a certain degree, inhibit the release of inflammatory factors in in vitro cell models; in animal experiments, it mildly promotes urine excretion in rats. Researchers are also exploring its potential blood-activating, stasis-dispersing action — but more human studies are still needed to verify whether these results can be applied clinically.

3. Limitations of Current Research

  • Lab results are not clinical efficacy — in vitro and animal results cannot be directly equated with the actual effect after human use; animal and human physiological mechanisms differ, and the experimental dose and environment also differ from daily use.
  • Extracts and monomers are not the same as traditional decoction pieces — modern research often uses extracts of single constituents, while traditional use is the dried whole-plant slice — the constituent composition and dose ratio differ completely; they cannot be directly converted.
  • Doses and preparation methods vary between studies — the extraction methods and administered doses of existing studies differ greatly, making it impossible to uniformly define an effective dose range, or to determine which preparation method better matches traditional application.
  • A single component does not define the whole herb — Dao Kou Cao's action is the joint result of many constituents; research on a single constituent cannot represent the whole herb's overall effect — discovering that one constituent has an anti-inflammatory action does not mean the whole herb can be used for all inflammation-related patterns.

Dao Kou Cao

Comparing Similar Herbs

1. What They Share

Choosing Tu Niu Xi as the similar herb — the two are close in both name and action — they share these points:

  • Both have the main actions of clearing and draining damp-heat, and activating blood to disperse stasis.
  • Both are used for the traditional patterns of damp-heat pouring downward and stasis blockage — such as difficult urination and fall-related swelling and pain.
  • Both need constitution and dose considered — neither fits those of a deficiency-cold constitution.

2. The Key Differences: Dao Kou Cao vs. Tu Niu Xi

  • Nature and flavors: Dao Kou Cao leans sinking, bitter-sour and cold, mainly clear-draining and stasis-dispersing; Tu Niu Xi is relatively more mild — the Tu Niu Xi of some regions leans sweet-insipid, with a certain auxiliary channel-freeing action besides clearing and draining. The two differ slightly in coldness — Dao Kou Cao's clear-drain action is stronger.
  • Focus: Dao Kou Cao is better at clearing the damp-heat of the lower jiao — more prominent for the difficult urination and lower-limb swelling pain of damp-heat; Tu Niu Xi is better at freeing the channels and activating blood — more fitting for the limb channel blockage and joint pain of falls and injuries. The two emphasize different parts.
  • Qi tendency: Dao Kou Cao's action leans sinking — mainly targeting the damp-heat and stasis of the lower jiao, draining the pathological products downward; Tu Niu Xi's action leans more channel-freeing — while activating blood, it helps free the qi movement of the channels — a scope leaning more to the limb channels.
  • Best fit: Dao Kou Cao's traditional indicators lean more to lower-jiao damp-heat signs — scanty dark urine, heavy lower limbs, and yellowing skin; Tu Niu Xi's indicators lean more to limb channel blockage signs — joint pain, limb numbness, and channel blockage after falls and injuries.
  • Not suitable: both are not for those of a deficiency-cold constitution, but Dao Kou Cao is colder — those who fear cold clearly are more unsuited; Tu Niu Xi is less cold — some with mild deficiency-cold can use a small amount under a physician's guidance, while Dao Kou Cao should be strictly avoided.
  • Use scenes: Dao Kou Cao is more used for the lower-jiao damp-heat patterns of damp-heat jaundice, beriberi swelling pain, and damp-heat-caused difficult urination; Tu Niu Xi is more used for the channel-blocked patterns of falls and injuries and joint pain, and for stasis amenorrhea in women.

3. One-Sentence Summary

Simply put, Dao Kou Cao leans toward clearing and draining the damp-heat of the lower jiao, whereas Tu Niu Xi leans toward freeing the channels and activating blood. Both can be used for damp-heat or stasis patterns, but they are not interchangeable.

Dao Kou Cao

Classical Formulas Containing Dao Kou Cao

Classic Formula 1: Dao Kou Cao Tang (Devil's-Horsewhip Decoction)

Combination logic: In this formula, Dao Kou Cao is the lord, carrying the core actions of clearing and draining damp-heat and activating blood to disperse stasis; Che Qian Zi and Ze Xie strengthen the clear-drain urination action; Hong Hua and Tao Ren strengthen the blood-activating, stasis-dispersing action; a small amount of Gan Cao harmonizes all the herbs and eases the coldness of the others. This formula mainly solves the difficult urination and lower-limb swelling pain of damp-heat pouring downward with stasis blockage. Because a single Dao Kou Cao's strength is limited and needs the synergy of several herbs, this herb should not be used alone.

Traditional use: traditionally used for the beriberi swelling pain and scanty dark urine of damp-heat pouring downward, and the lower-limb stasis swelling pain after falls and injuries — a classic formula commonly used in folk practice for clearing lower-jiao damp-heat.

Modern note: modern clinical use requires the doctor's pattern diagnosis and standard care — do not self-apply just because the formula name relates to lower-limb swelling pain; the physician must adjust the dose and combination to your pattern.

Classic Formula 2: Dao Kou Cao Tui Huang Fang (Devil's-Horsewhip Jaundice-Resolving Formula)

Combination logic: In this formula, Dao Kou Cao is a minister, assisting the lord Yin Chen in clearing and draining damp-heat to resolve jaundice, while also exerting its own blood-activating action; Zhi Zi strengthens the heat-clearing, dampness-draining effect; Fu Ling strengthens the spleen and percolates dampness, preventing damp-heat from blocking the spleen and stomach. Yin Chen is the lord; Dao Kou Cao assists its clear-drain and blood-activating action, jointly solving the problem of damp-heat jaundice.

Traditional use: traditionally used for damp-heat jaundice — shown as yellowing skin, scanty dark urine, and abdominal fullness — a classic formula for jaundice assistance in folk practice.

Modern note: modern clinical use requires the doctor's pattern diagnosis and standard care. Jaundice has many causes — do not self-use this formula; the physician must identify the cause before guiding its use.

Formulas vs. Single Herbs

A formula is a whole of many herbs acting together — every herb's dose and combination are designed for the overall pattern. A single Dao Kou Cao cannot simply replicate a full formula's effect, because the other herbs in the formula can strengthen or harmonize the nature, while a single herb's action is relatively single. To be clear: a herb that works in a formula does not mean taking it alone produces the same effect — a formula's action is the synergy of many herbs; taking a single herb alone may not reach the same effect, and may even bring discomfort from improper dose or combination. Do not build formulas from online articles — use under a physician's guidance.

Diet & Daily Home Use

1. Home Tea

Tea — Dao Kou Cao Qing Li Shi Re Cha (Damp-Heat-Clearing Tea): Dao Kou Cao slices 5 g, Che Qian Zi 3 g, Fu Ling 2 g. Wrap all the materials in gauze, put into a teapot, steep in boiling water, cover 10 minutes, and drink; it can be re-steeped 2–3 times. Suited to the light damp-heat signs of a heavy summer damp-heat period — scanty dark urine, mild lower-limb swelling, and a heavy body. Not for those of a deficiency-cold constitution, pregnant women, or women with heavy menstrual flow. Suggested: 2–3 times a week, 1 cup each time; do not drink long-term continuously. Note: Dao Kou Cao is a medicinal slice — do not treat it as an ordinary food and add it casually; confirm your constitution fits before drinking.

2. Decoction and Processing Differences

The raw Dao Kou Cao has a stronger clear-drain action — fitting for regulating more obvious damp-heat signs; the processed has a somewhat eased coldness — fitting for those with a somewhat weaker constitution but still some damp-heat. At home, Dao Kou Cao is an ordinary slice needing no special handling — put it into the pot with the other materials, add proper clean water, soak 20 minutes, boil over high heat, then turn to low heat and cook 15 minutes. Different forms cannot be converted directly — for example, the dose of the slice differs greatly from that of the extract; do not replace the slice dose with the extract dose.

3. Dosage and Course

The common dose in traditional prescriptions is 10–15 g; the food-therapy dose is usually 3–6 g — smaller than the medicinal dose. Long-term continuous use is not advised — the general regulation course is 3–5 days; stop once the symptoms ease. Special groups — such as children, the elderly, and pregnant women — should consult a physician or pharmacist before use; do not adjust the dose and course on your own.

Dao Kou Cao

Contraindications & Safety Warnings

1. Who Should Avoid It

  • Deficiency-cold constitution — people who usually fear cold, have cold hands and feet, and loose stool should not use it, to avoid worsening the deficiency-cold.
  • Pregnancy and breastfeeding — currently no sufficient safety research data — it is advised to avoid use.
  • Children and the elderly — weaker body metabolism — use under a physician's guidance; do not self-take.
  • Liver or kidney impairment — the herb needs liver-kidney metabolism and may add to the liver-kidney burden — consult a doctor before considering use.
  • Allergy to Dao Kou Cao or Amaranthaceae plants — avoid use, to prevent allergic reactions.

2. Interactions and Diet Notes

Dao Kou Cao may interact with anticoagulants, blood-pressure medications, and glucose-lowering medications — for example, it may strengthen the anticoagulant effect and increase the bleeding risk, or affect the blood-pressure-lowering effect of antihypertensives. Those taking such drugs should consult a doctor or pharmacist first to confirm whether it can be used. There is no sufficient evidence of a general "food clash" between ordinary foods, but certain herbs can interact with specific drugs — those on medication should consult a doctor or pharmacist first; do not pair food or drugs on your own.

3. Adverse Reactions and Overdose Risk

Dao Kou Cao has relatively few adverse reactions, but overdose may cause spleen-stomach discomfort — nausea, vomiting, and diarrhea. If marked discomfort, allergy signs (such as rash, itching, or breathing difficulty), persistent vomiting, altered consciousness, or rapidly worsening symptoms appear, stop at once and seek medical care — do not self-treat.

Frequently Asked Questions About Dao Kou Cao

What is Daokoucao? Is it the same as Niuxi or Jigucao?
Daokoucao is the dried whole plant of Achyranthes aspera, Latin name Achyranthis Asperae Herba. It is a common Chinese medicine centered on activating blood and transforming stasis, promoting urination to relieve strangury, and clearing heat to release the exterior. Niuxi activates blood and unblocks meridians while tonifying the liver and kidney. Jigucao drains dampness and clears jaundice for the liver and gallbladder. They cannot be used interchangeably in equal amounts. Prescribe as Daokoucao. Caution in pregnancy.
What are the composition and effects of Daokoucao?
Pharmacopoeial name Daokoucao, Latin Achyranthes aspera L. Bitter and sour in taste, slightly cold in nature, enters the Liver, Lung and Bladder meridians. Functions to activate blood and transform stasis, promote urination to relieve strangury, and clear heat to release the exterior. Used for amenorrhea, dysmenorrhea, irregular menstruation, traumatic injuries, wind-damp joint pain, strangury, edema, damp-heat leukorrhea, and external contraction fever. Activates blood and promotes urination.
How to choose between raw and processed? Can Niuxi replace it?
Whole plant is used raw. Niuxi emphasizes tonifying the liver and kidney rather than strongly clearing heat, and cannot replace it in equal amounts. Commercial products are standardized; do not adjust arbitrarily.
What is the dosage of Daokoucao? Can it be used daily as a blood-activating tea?
Decoction, 15-30g. Modern use requires physician-determined dosage. It is not a year-round "Daokoucao tea." Pregnancy will be further injured by prolonged use. Amenorrhea requires short-term, physician-determined dosage and cannot replace evaluation.
What are the contraindications of Daokoucao? Can pregnant women use it?
Not suitable for pregnant women. Stop if loose stools or abdominal pain occur. Seek immediate medical care for severe bleeding or high fever.
Can Daokoucao activate blood, promote urination, and clear heat?
It can assist amenorrhea, dysmenorrhea, irregular menstruation, traumatic injuries, wind-damp joint pain, strangury, edema, damp-heat leukorrhea, and external contraction fever. It activates blood and transforms stasis, promotes urination to relieve strangury, and clears heat to release the exterior, but is not a specific remedy for all amenorrhea or all strangury.
Can Daokoucao be taken daily as a blood-activating or strangury-relieving tea?
Blood stasis with strangury can be used short-term in formulas; pregnancy will be further injured. The idea that "Daokoucao must activate blood" cannot replace evaluation. Activating blood and promoting urination requires physician-determined formulation and dosage.
How to choose between Daokoucao, Niuxi, Jigucao, Yimucao, and Cheqiancao?
Daokoucao activates blood and promotes urination, suited to amenorrhea and strangury. Niuxi activates blood and unblocks meridians while tonifying the liver and kidney. Jigucao drains dampness and clears jaundice. Yimucao activates blood and regulates menstruation. Cheqiancao clears heat and promotes urination. Choose Daokoucao for activating blood; Niuxi for unblocking meridians; Jigucao for clearing jaundice; Yimucao for regulating menstruation; Cheqiancao for promoting urination. Pattern differentiation applies, but large doses of Daokoucao are contraindicated in pregnancy.
How is Daokoucao commonly modified? What is a representative usage?
Modifications depend on the pattern. Add Yimucao for amenorrhea; add Cheqianzi for strangury. Specify Daokoucao; do not substitute Niuxi in equal amounts for promoting urination.
How to select and store Daokoucao?
Choose regular Chinese medicinal materials with intact whole plants. Discard if moldy, damp, or abnormal in odor. Store in a dry place. Purchase "Daokoucao"; do not substitute Niuxi or Jigucao in equal amounts for activating blood, promoting urination, and clearing heat.

Medical Disclaimer — This article is provided for educational purposes only and describes traditional Chinese medicine concepts. It is not medical advice, and it is not intended to diagnose, treat, cure or prevent any disease. Always consult a qualified practitioner before using any herb, particularly if you are pregnant, nursing, taking medication or managing a diagnosed condition.

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Dao Kou Cao (Rough Achyranthes Herb): Clears heat, releases the exterior, promotes urination, and invigorates blood