Whole herbsHeat-clearingBidentis Herba

Gui Zhen Cao (Spanishneedle Herb)

A practical guide to Gui Zhen Cao: what it is, how Traditional Chinese Medicine uses it, the classical formulas it appears in, and who should be careful with it.

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Last reviewed Oct 29, 2026

Quick Facts

Latin NameBidentis Herba
Chinese Name & Pinyin 鬼針草 · Gui Zhen Cao
Medicinal PartWhole herbs
The itemGui Zhen Cao is the dried above-ground part of the hairy beggarticks plant. Jin Yin Hua (honeysuckle flower) and the daisy-family look-alike plants are not this drug.
Nature and channelsFlat, bitter. Enters the Liver, Lung, and Large Intestine. Flat bitter clears heat and toxin, invigorates the blood, and disperses swelling.
Pharmacopoeia lineClears heat and resolves toxin; dispels wind and damp; invigorates the blood and disperses swelling. Used for damp-heat diarrhea, sore throat, skin sores, and bruise-swelling.
Pattern cuesSticky smelly stools. Burning anus. Swollen sore throat. Skin sores and boils. Bruise-swelling. Joint swelling. Heavy limbs.
In this articleGui Zhen Cao versus Jin Yin Hua. Clearing damp-heat and dispersing swelling versus clearing heat and dispersing wind-heat. Why cold-weak spleens should skip it. Home tea and external wash.

What Is Gui Zhen Cao?

Gui Zhen Cao (鬼针草; Guǐ Zhēn Cǎo; Latin: Bidentis Herba; English: hairy beggarticks) is the dried above-ground part of a daisy-family annual herb whose small barbed seed-heads cling to trouser legs and fur and travel wherever they please — the cheerful "sticky weed" of summer roadsides. It is flat, bitter, enters the Liver, Lung, and Large Intestine channels, and its core actions are to clear heat and resolve toxin, and to invigorate the blood and disperse swelling. It is the plain summer herb for damp-heat looseness and for bruises. The usual amount is 10–15 g in a decoction, or a suitable amount for external use. Soak the pieces 30 minutes and boil 20–30 minutes — no special first, last, or wrapped step. It is a medicinal piece, not a food to add to daily meals.

It is not Jin Yin Hua. Honeysuckle flower is cold and sweet — it clears heat and disperses wind-heat, better for marked heat-toxin or a wind-heat cold; this beggarticks herb is flat and bitter — it clears damp-heat, moves blood, and disperses swelling, better for damp-heat with stasis and local bruise-swelling. It is not a catch-all heat herb; it acts within clear patterns. In a cold-weak spleen-stomach — a belly that fears cold, loose stools, cold hands and feet — or in pregnancy, using it on your own is a poor match. Persistent diarrhea or an unhealed sore needs a clinic first. Do not take it yourself for a long time.

It is used most often for three patterns:

  • Damp-heat with heat toxin — sticky smelly stools, burning anus, a swollen sore throat, skin sores and boils
  • Blood stasis and swelling — bruise-swelling and pain from falls, joint swelling from wind-damp
  • Cold-weak spleen-stomach without damp-heat — or pregnancy — seek care / skip it

Flat, bitter, and clearing, it is not a daily "damp-clearing weed tea" to keep drinking. Clearing when there is no damp-heat, or in a cold body, drains the upright qi instead of helping.

When heat-toxin and damp gather — the stools turn sticky, the throat swells, sores appear, or a fall leaves purple swelling — the body needs a steady clear-and-disperse rather than a strong purge. Gui Zhen Cao is flat and bitter. It clears the heat and toxin, drains the damp, and disperses the stasis and swelling, which is why it appears in Gui Zhen Cao Tang (Beggarticks Decoction)–type formulas. It clears more than it holds. In a cold-weak spleen-stomach, or without damp-heat and stasis, more makes it worse.

Gui Zhen Cao is not a catch-all damp or heat weed. In a cold-weak spleen-stomach, in pregnancy, or without damp-heat and stasis, using it alone is a poor match. Whether it belongs in a formula, and at what dose, should be decided by a licensed Chinese medicine practitioner after pattern diagnosis.

Gui Zhen Cao

Gui Zhen Cao: Materia Medica Profile

Identification & Quality Standard

Bidentis Herba

Botanical Origin

The dried aerial part of Bidens pilosa L., Bidens bipinnata L. or Bidens biternata (Lour.) Merr. et Sherff (Asteraceae).

Production Regions

Produced in most areas of China.

Quality Requirements

Superior medicinal material is greenish, leafy, flowered.

Macroscopic Features

Stems are quadrangular, often branched, 30~100cm long; externally yellowish-brown or green. Leaves opposite, pinnately divided, often shrunken; leaflets are ovate, margin serrate. Capitula terminal; achenes linear, with 2~3 awns at apex. Faint odor, taste bitter.

Main Regions and Quality Identification

Classic texts and trade experience favor plants from several provinces — the weed grows across most of the country, with the southern origin plants usually sturdier and leafier and the northern origin plants smaller. Good Gui Zhen Cao shows a green-brown stem with a hollow or white-pith center; intact, dark-green leaves without yellowing or rot; and clear flower heads without impurities. The common look-alike is a same-genus plant with more obvious leaf-edge teeth and two fruit bristles — tell them apart by shape.

Traditional Properties & Historical Lineage

Nature, Flavour & Channel Tropism

Bitter; NeutralLiverLungLarge Intestine

1. Records in Classic Materia Medica

  • Ben Cao Gang Mu Shi Yi: "resolves various toxins; is used for snake bites."
  • Zhong Hua Ben Cao: "clears heat and resolves toxin, dispels wind and damp, invigorates the blood and disperses swelling."
  • Zhi Wu Ming Shi Tu Kao: also records use for malaria and diarrhea in older practice.

These records center on clearing, draining, and stasis-dispersing — no modern efficacy conclusions.

2. How Views of Its Nature Changed

Some doctors leaned on clearing heat and resolving toxin — for febrile heat and bowel complaints; others stressed dispelling wind-damp and invigorating the blood — for joint pain and injuries from falls; still others noticed its calm nature — clearing without readily damaging the upright qi — but were clear that it does not fit cold-weak spleens without damp-heat and stasis, and should not be taken as a general tonic or clearing herb.

Gui Zhen Cao

Core Efficacies & Traditional Applications

Traditional Functions

Clears heat and resolves toxin, disperses stasis and reduces swelling.

1. Main Use 1: Clearing Heat and Resolving Toxin

(1) Traditional action: clearing heat and resolving toxin — removing damp-heat and heat-toxin from the body. (2) Typical patterns: damp-heat diarrhea and dysentery — sticky smelly stools, a burning anus; heat-toxin — a swollen sore throat, skin sores and boils with red swollen painful skin. (3) Usual pairings: Huang Lian and Huang Qin to strengthen the heat- and damp-clearing; Jin Yin Hua and Pu Gong Ying to strengthen the toxin-resolving and swelling-dispersing. (4) Not for self-use: cold-weak spleen-stomach — a belly that fears cold, thin loose stools, cold hands and feet.

2. Main Use 2: Invigorating the Blood and Dispersing Swelling

(1) Traditional action: moving the stasis in the channels and easing the swelling and pain. (2) Typical patterns: bruise-swelling from falls — local purple swelling and fixed pain; wind-damp joint swelling with limited movement that worsens in cold. (3) Usual pairings: Hong Hua and Tao Ren to strengthen the blood-moving and stasis-dispersing; Du Huo and Wei Ling Xian for wind-damp joint pain. (4) Not for self-use: pregnancy — blood-moving herbs may affect the pregnancy.

3. A Classic Pairing

Gui Zhen Cao pairs classically with Jin Yin Hua: the beggarticks clears damp-heat, moves blood, and resolves toxin; the honeysuckle clears heat and resolves toxin and disperses wind-heat — together they strengthen the heat-clearing, toxin-resolving, and swelling-dispersing for damp-heat heat-toxin — a swollen sore throat, skin sores and boils, mild dysentery. This pair belongs to a practitioner's pattern diagnosis — no casual self-pairing.

Gui Zhen Cao

Modern Research

Modern research offers useful context, but Traditional Chinese Medicine prescribes on whole-pattern diagnosis rather than isolated compounds.

1. Main Chemical Constituents

Detected in the plant are flavonoids (luteolin, apigenin), volatile oils (pinene, limonene), organic acids (chlorogenic acid), and saponins. In vitro, these constituents show some anti-inflammatory activity and inhibit the release of some inflammatory factors; in animals, the extract lowers experimental fever and regulates intestinal movement in mice. No sufficient human clinical study yet reaches a clear efficacy conclusion.

2. Current Research Directions

Current work centers on anti-inflammation and immune regulation — some in-vitro and animal experiments show improvement in several inflammatory models; other research looks at digestive function. These studies are mostly at a preliminary stage and still need human verification.

3. Limitations of Current Research

  • Lab results are not clinical efficacy — component effects may differ from the piece's effect in people.
  • Extracts are not decoction pieces — experimental doses cannot be converted to the piece dose.
  • Doses and preparations vary between studies — results are hard to compare.
  • One component does not define the whole herb — the plant acts as a team of constituents.

Gui Zhen Cao

Comparing Similar Herbs

1. What They Share

  • Both clear heat and resolve toxin.
  • Both are used for heat-toxin patterns — a swollen sore throat and skin sores.
  • Both need constitution and dose care — cold-weak spleens should be cautious.

2. Key Differences

Nature and flavor: Gui Zhen Cao is flat and bitter — neither cold nor hot, calm enough for longer small use without readily harming the upright qi; Jin Yin Hua is cold and sweet — its heat-clearing is stronger, and overuse or long use may chill the spleen yang — a belly that fears cold and loose stools. Focus: Gui Zhen Cao also invigorates the blood and disperses swelling — for bruise-swelling from falls and wind-damp joint swelling; Jin Yin Hua mainly clears heat and resolves toxin, and also disperses wind-heat — for fever, headache, and a swollen sore throat in wind-heat colds, without a marked blood-moving side. Tendency: Gui Zhen Cao descends and sinks inward — clearing the lower damp-heat and freeing the channel stasis without much effect on the surface qi; Jin Yin Hua ascends and scatters outward — dispersing the surface wind-heat and easily moving the surface qi. Best fit: Gui Zhen Cao for damp-heat with stasis — damp-heat diarrhea with abdominal distension, skin sores with local stasis lumps; Jin Yin Hua for pure heat-toxin or wind-heat surface patterns — fever with a swollen sore throat and no stasis signs. Who should avoid: Gui Zhen Cao — pregnancy and cold-weak spleens without clear damp-heat; Jin Yin Hua — cold-weak spleens and yang-deficient bodies — always cold, marked fear of cold — the cold nature may worsen the yang deficiency. Where you meet them: Gui Zhen Cao in damp-heat-stasis formulas, external care for injuries from falls, and daily light teas; Jin Yin Hua in wind-heat or heat-toxin sore formulas — more for early colds or marked heat-toxin.

3. One-Line Takeaway

In short, Gui Zhen Cao clears damp-heat and disperses blood-swelling; Jin Yin Hua clears heat-toxin and disperses wind-heat. Both can serve heat-toxin discomfort — but they are not stand-ins for each other.

Gui Zhen Cao

Classical Formulas Containing Gui Zhen Cao

Classic Formula 1: Gui Zhen Cao Tang

Role of this herb: in Gui Zhen Cao Tang (Beggarticks Decoction), Gui Zhen Cao is the monarch — clearing heat, resolving toxin, and dispersing swelling — with Jin Yin Hua and Pu Gong Ying strengthening the toxin-resolving and with Dang Gui and Hong Hua strengthening the blood-moving and stasis-dispersing, together for damp-heat stasis — bowel complaints, bruise-swelling from falls. Alone, it cannot cover the toxin-resolving and blood-moving of the whole pattern. Traditional focus: damp-heat stasis — bowel complaints, injuries from falls, skin sores — easing local swelling, fever, and sticky stools. Modern note: professional diagnosis first — never self-apply by the name to a modern illness.

Classic Formula 2: Qing Chang Yin

Role of this herb: in Qing Chang Yin (Intestine-Clearing Decoction), Gui Zhen Cao is a supporting herb — assisting the monarch Huang Lian in clearing the intestinal damp-heat — with Mu Xiang and Bing Lang sorting the intestinal qi and easing pain and diarrhea — for damp-heat dysentery with abdominal pain, diarrhea, and a sense of urgency. Traditional focus: damp-heat dysentery — stools with pus and blood, bearing-down abdominal pain, a burning anus. Modern note: professional diagnosis first — never self-apply.

Formula vs. Single Herb

A formula is a coordinated whole — the monarch-minister pairing lets herbs reinforce and check one another, and a single herb cannot reproduce the full effect; the dose and pairing of a formula are a unity. The common misunderstanding is that a herb that works in a formula will work the same way alone — that does not follow the whole-use principle of Chinese medicine. Do not self-formulate from web articles.

Diet & Daily Home Use

1. Home Tea and External Use

Example 1 — Gui Zhen Cao summer tea: dried Gui Zhen Cao 10 g, Jin Yin Hua 5 g, a little rock sugar — rinse, put in a teapot, add boiling water, cover 10 minutes, sweeten. Fit: light summer damp-heat — slight swollen sore throat, sticky stools, or a hot stuffy feeling after outdoor work. Not for: cold-weak spleen-stomach or pregnancy. Frequency: 1–2 times a week; no long continuous use. Example 2 — external bruise liquid: fresh Gui Zhen Cao 30 g, a little white liquor — mash the fresh herb, mix with the liquor, and apply to the bruised swollen spot. Fit: light bruise-swelling without broken skin. Not for: broken skin, or allergy to alcohol or the herb. Frequency: once a day, no more than 3 days.

2. Decoction and Processing Differences

The raw piece is the common form — no special processing. At home, rinse the pieces, put them in a clay pot, soak in clean water 30 minutes, then decoct; no first, last, wrapped, or dissolve-last step — 20–30 minutes of boiling is enough. Different forms cannot be converted directly — a dried-piece dose differs greatly from a fresh-plant dose; do not convert by ratio on your own.

3. Dosage and How Long to Use

The classic range is 10–15 g in formulas, with a suitable amount for external use; food-remedy amounts are about half the medicinal dose. No long continuous use — generally for light care, no more than 1 week. Special groups — pregnancy, children, liver or kidney impairment — consult a practitioner or pharmacist first.

Gui Zhen Cao

Contraindications & Safety Warnings

1. Who Should Avoid It

Cold-weak spleen-stomach — a belly that fears cold, thin loose stools, cold hands and feet — avoid; pregnancy and nursing — be cautious; children and the elderly — weaker bodies, use under a practitioner; liver or kidney impairment — no self-use; allergy to the daisy family — may react, be cautious; people on anticoagulant, blood-pressure, blood-sugar, or sedative therapy — consult a doctor first.

2. Interactions and Diet Notes

No blanket "food clash" between ordinary foods is established, but certain herbs may interact with specific medicines — with an anticoagulant, monitor the blood-clotting function; with blood-pressure or blood-sugar medicines, the dose may need adjustment to avoid swings. People on medication should consult a doctor or pharmacist first.

3. Side Effects and Overuse

Overuse may bring stomach discomfort, nausea, vomiting, or diarrhea; some people may show rash or itching as an allergic reaction. Stop and seek care at once for marked discomfort, an allergic reaction, persistent vomiting, trouble breathing, confusion, or a rapid worsening of symptoms.

Frequently Asked Questions About Gui Zhen Cao

What is Guizhencao? Is it the same as Sanye Guizhencao or Pugongying?
Guizhencao is the dried whole plant of Bidens pilosa, Latin name Bidentis Herba. It is a common Chinese medicine centered on clearing heat and detoxifying, and dispersing stasis and activating blood. Sanye Guizhencao is related. Pugongying clears heat and detoxifies while reducing swelling. They cannot be used interchangeably in equal amounts. Prescribe as Guizhencao. Caution in spleen-stomach deficiency cold.
What are the composition and effects of Guizhencao?
Pharmacopoeial name Guizhencao, Latin Bidens pilosa L. Bitter in taste, slightly cold in nature, enters the Lung, Stomach and Large Intestine meridians. Functions to clear heat and detoxify, and disperse stasis and activate blood. Used for swollen and painful throat, diarrhea, dysentery, jaundice, intestinal abscess, boils and abscesses with swelling and toxicity, snake and insect bites, and traumatic injuries. Clears heat and activates blood.
How to choose between raw and processed? Can Pugongying replace it?
Whole plant is used raw. Pugongying emphasizes reducing swelling rather than strongly activating blood, and cannot replace it in equal amounts. Commercial products are standardized; do not adjust arbitrarily.
What is the dosage of Guizhencao? Can it be used daily as a heat-clearing tea?
Decoction, 15-30g. Modern use requires physician-determined dosage. It is not a year-round "Guizhencao tea." Spleen-stomach deficiency cold will be further injured by prolonged use. Sore throat requires short-term, physician-determined dosage and cannot replace evaluation.
What are the contraindications of Guizhencao? Can pregnant women use it?
Not suitable for spleen-stomach deficiency cold. Pregnant women require physician evaluation. Stop if loose stools or abdominal pain occur. Seek immediate medical care for severe sore throat or high fever.
Can Guizhencao clear heat, detoxify, and activate blood?
It can assist swollen and painful throat, diarrhea, dysentery, jaundice, intestinal abscess, boils and abscesses with swelling and toxicity, snake and insect bites, and traumatic injuries. It clears heat and detoxifies, and disperses stasis and activates blood, but is not a specific remedy for all sore throat or all trauma.
Can Guizhencao be taken daily as a heat-clearing or blood-activating tea?
Heat toxicity can be used short-term in formulas; spleen-stomach deficiency cold will be further injured. The idea that "Guizhencao must clear heat" cannot replace evaluation. Clearing heat and activating blood requires physician-determined formulation and dosage.
How to choose between Guizhencao, Sanye Guizhencao, Pugongying, Jinyinhua, and Honghua?
Guizhencao clears heat and activates blood, suited to sore throat. Sanye Guizhencao is related. Pugongying clears heat and reduces swelling. Jinyinhua clears heat and disperses. Honghua activates blood and unblocks the channels. Choose Guizhencao for clearing heat; Pugongying for reducing swelling; Jinyinhua for dispersing; Honghua for unblocking the channels. Pattern differentiation applies, but large doses of Guizhencao are contraindicated in spleen-stomach deficiency cold.
How is Guizhencao commonly modified? What is a representative usage?
Modifications depend on the pattern. Add Jinyinhua for sore throat; add Honghua for trauma. Specify Guizhencao; do not substitute Pugongying in equal amounts for activating blood.
How to select and store Guizhencao?
Choose regular Chinese medicinal materials with intact whole plants. Discard if moldy, damp, or abnormal in odor. Store in a dry place. Purchase "Guizhencao"; do not substitute Pugongying or Jinyinhua in equal amounts for clearing heat, detoxifying, and activating blood.

Medical Disclaimer — This article is provided for educational purposes only and describes traditional Chinese medicine concepts. It is not medical advice, and it is not intended to diagnose, treat, cure or prevent any disease. Always consult a qualified practitioner before using any herb, particularly if you are pregnant, nursing, taking medication or managing a diagnosed condition.

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Gui Zhen Cao (Spanishneedle Herb): Clears heat, resolves toxicity, disperses stasis, and reduces swelling