Chai Hu Shu Gan San

Classical TCM Formula Profile

Part of the HJMEDICAL TCM Discovery Center

柴胡疏肝散 · Chái Hú Shū Gān Sǎn

A focused Qi-regulating formula for Liver Qi stagnation with pain (especially hypochondriac or epigastric). Stronger moving action than Xiao Yao San and without significant Blood or Spleen tonification.

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Quick Facts

Formula Category
Qi-Regulating Formulas
Primary Pattern
Qi Stagnation
Primary Function
Course Liver Qi, regulate Qi, stop pain
Primary Therapeutic Principle
Course the Liver, regulate Qi and relieve pain
Classical Source
Jing Yue Quan Shu (Complete Works of Jingyue, Ming dynasty)
Available as Granules
Yes

Formula Overview

A focused Qi-regulating formula for Liver Qi stagnation with pain (especially hypochondriac or epigastric). Stronger moving action than Xiao Yao San and without significant Blood or Spleen tonification.

Therapeutic Principle

Traditionally selected for pure Liver Qi stagnation where pain is the leading complaint — hypochondriac distension and epigastric discomfort — moving Qi more forcefully than Xiao Yao San and Jia Wei Xiao Yao San, which are better suited to longer-standing patterns complicated by Blood deficiency and Spleen weakness.

Composition: Sovereign, Minister, Assistant, Envoy

Every herb in the formula, grouped by the job it does in the classical hierarchy.

Classical Composition

  • Radix Bupleuri (Chai Hu) 6g
  • Fructus Aurantii (Zhi Ke) 6g
  • Rhizoma Cyperi (Xiang Fu) 6g
  • Rhizoma Chuanxiong (Chuan Xiong) 6g
  • Radix Paeoniae Alba (Bai Shao) 9g
  • Radix et Rhizoma Glycyrrhizae Praeparata cum Melle (Zhi Gan Cao) 3g
  • Pericarpium Citri Reticulatae (Chen Pi) 6g

Dosages follow the classical source and are shown for study, not as a prescription.

Related Conditions

Related Health Topics

Actions

  • Courses the liver
  • moves qi
  • invigorates blood and relieves pain.

Indications

  • This formula is indicated for constrained liver qi with blood stasis in the chest and flanks.
  • Signs and symptoms include rib-side and chest distending pain, belching, depression or irritability, and a wiry pulse.
  • Pain often fluctuates with the emotions.

Traditional Pathogenesis

Cause & mechanism

  • This pattern is caused by constrained qi that fails to course freely through the liver and middle jiao.
  • Stagnation produces distension that moves with the emotions, rib-side tightness, belching or irregular menstruation.
  • Constrained liver qi with blood stasis in the chest and flanks produces moving distending pain; the formula courses qi more strongly than Xiao Yao San and does not emphasise blood nourishment.

Treatment strategy

  • The correct method is to course the liver, move qi, and resolve constraint.
  • In this formula the emphasis is to course the Liver, regulate Qi and relieve pain.

How does this formula compare?

Compare Chai Hu Shu Gan SanSi Ni SanXiao Yao SanXue Fu Zhu Yu TangJia Wei Xiao Yao San
Primary Function Course Liver Qi, regulate Qi, stop painCourse Liver Qi, resolve constraint, harmonizeCourse Liver Qi, tonify Spleen, nourish BloodInvigorate Blood, dispel stasis, move QiCourse Liver Qi, clear Heat, tonify Spleen and Blood
Formula Category Qi-Regulating FormulasHarmonising FormulasHarmonising FormulasBlood-Invigorating FormulasHarmonising Formulas
Typical TCM Pattern Qi StagnationQi StagnationQi StagnationBlood StasisQi Stagnation
Main Conditions Hypochondriac Distension·Bloating·Emotional Depression·Chest TightnessCold Limbs·Hypochondriac Distension·Bloating·Emotional DepressionHypochondriac Distension·Emotional Depression·Poor Appetite·Irregular MenstruationChest Tightness·Headache·Hypochondriac Distension·Emotional DepressionHypochondriac Distension·Anxiety Restlessness·Irregular Menstruation·Emotional Depression
Main Herbs Bupleurum Root·Cyperus Rhizome·Chuanxiong Rhizome·Bitter Orange·White Peony RootBupleurum Root·Immature Bitter Orange·White Peony Root·Honey-fried LicoriceBupleurum Root·Chinese Angelica Root·White Peony Root·White Atractylodes Rhizome·Poria / HoelenPeach Kernel·Safflower·Chinese Angelica Root·Raw Rehmannia Root·Chuanxiong RhizomeBupleurum Root·Chinese Angelica Root·White Peony Root·White Atractylodes Rhizome·Poria / Hoelen
Classical Source Jing Yue Quan Shu (Complete Works of Jingyue, Ming dynasty)Shang Han Lun (Zhang Zhongjing, Eastern Han)Tai Ping Hui Min He Ji Ju Fang (Song dynasty)Yi Lin Gai Cuo (Corrections of Errors in Medical Classics, Wang Qingren, Qing dynasty)Nei Ke Zhai Yao (Summary of Internal Medicine, Ming dynasty) / also known as Dan Zhi Xiao Yao San

Clinical Perspective

Chai Hu Shu Gan San is preferred for pure Qi stagnation with marked pain. Xiao Yao San and Jia Wei Xiao Yao San address constraint together with Blood deficiency and Spleen weakness, and are better for longer-term or deficient patients.

Clinical Differentiation

  • Chai Hu Shu Gan San is used for constrained liver qi with more moving, distending pain than Xiao Yao San addresses.
  • It courses qi more strongly and does not emphasise blood nourishment or spleen support.
  • It is distinguished from Yue Ju Wan, which treats mixed constraint of several pathogens rather than liver qi alone.

Tongue & pulseThe pattern is rib-side or chest pain that fluctuates with emotion, and a wiry pulse.

Safety notes: This formula courses and moves. It is not appropriate for liver-blood or yin deficiency without stagnation, and should not be used as a long-term tonic.

For educational reference only, based on traditional pattern differentiation — not a substitute for professional advice.

Frequently Asked Questions

What are the actions of Chai Hu Shu Gan San?
Chai Hu Shu Gan San has the actions of spreading Liver Qi, invigorating Blood, and alleviating pain. It is primarily used for Liver Qi stagnation patterns with hypochondriac or chest distending pain, emotional constraint, irritability, and a wiry pulse.
Which modern diseases is Chai Hu Shu Gan San suited to?
Modern TCM clinical practice commonly applies it to individuals whose pattern differentiation falls within Liver Qi stagnation, including stress-related depression or anxiety, chronic gastritis, irritable bowel syndrome with emotional triggers, hypochondriac pain, and menstrual pain from Qi stagnation.
Is Chai Hu Shu Gan San suitable for improving chest or rib-side pain and irritability?
For presentations of distending pain in the chest or hypochondrium, emotional frustration or irritability, frequent sighing, epigastric fullness, and a wiry pulse — in those whose pattern differentiation confirms Liver Qi stagnation — TCM commonly applies Chai Hu Shu Gan San as an adjunct. It cannot replace standard medical treatment.
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Medical Disclaimer

For general TCM education only — not medical advice. Consult a qualified TCM practitioner or licensed healthcare provider before use, especially if pregnant, nursing, on medication, or managing a chronic condition.

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