Qi-Tonifying Formulas

归脾汤 · Guī Pí Tāng

Gui Pi Tang

A classical formula for Spleen Qi and Heart Blood deficiency from overthinking, with insomnia, palpitations, fatigue, poor appetite and possible spotting or pale menstruation.

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Last reviewed August 2026
Formula CategoryQi-Tonifying Formulas
Primary PatternQi Deficiency
Primary FunctionTonify Qi and Blood, strengthen Spleen, nourish the Heart
Primary Therapeutic PrincipleStrengthen Spleen Qi and nourish Heart Blood to calm the spirit
Main HerbsGinseng Root · Astragalus Root · White Atractylodes Rhizome · Poria / Hoelen · Sour Jujube Seed · Longan Aril · Aucklandia / Costus Root · Chinese Angelica Root · Polygala Root · Honey-fried Licorice
Classical SourceJi Sheng Fang (Yan Yonghe, Song dynasty)

Why This Formula?

Traditionally selected when overthinking has damaged Spleen and Heart — insomnia and fatigue with digestive weakness — rather than pure Middle-raising or general dual tonification.

Traditionally selected when overthinking has damaged Spleen and Heart — insomnia and fatigue with digestive weakness — rather than pure Middle-raising or general dual tonification.

What Is Gui Pi Tang?

1. Records & Background

Gui Pi Tang (归脾汤), or Restore the Spleen Decoction, is a classical formula first recorded in Yan Yong-he’s Ji Sheng Fang and later refined in the Ming dynasty. It belongs to the category of formulas that tonify Qi and Blood while strengthening the Spleen and nourishing the Heart.

This formula addresses Heart and Spleen Qi and Blood deficiency, commonly arising from excessive worry or overthinking that depletes both the Spleen’s generative function and the Heart’s ability to house the spirit. Typical signs include fatigue and weakness, poor appetite, palpitations, insomnia or dream-disturbed sleep, forgetfulness, anxiety, pale complexion, and in some cases easy bruising or abnormal bleeding due to the Spleen’s failure to hold Blood.

Combining Ren Shen and Huang Qi to tonify Qi, Bai Zhu and Fu Ling to strengthen the Spleen, Long Yan Rou and Suan Zao Ren to nourish Heart Blood and calm the spirit, Dang Gui to further enrich Blood, Yuan Zhi to promote Heart-Kidney communication, and a small amount of Mu Xiang to regulate Qi and prevent stagnation, Gui Pi Tang effectively restores the Spleen, nourishes the Heart, and settles the mind.

Gui Pi Tang

2. Cardiovascular System Diseases

  • For patients dealing with conditions like coronary heart disease or arrhythmias, this formula is highly beneficial if their underlying pattern is a Heart and Spleen deficiency.
  • Symptom Relief: Gui Pi Tang effectively improves uncomfortable symptoms such as palpitations, chest tightness, and shortness of breath.
  • By boosting Qi, building blood, strengthening the Spleen, and nourishing the Heart, it enhances overall cardiac function and helps regulate the smooth flow of energy and blood to the heart.

3. Neurological System Diseases

  • When conditions like neurasthenia (nervous exhaustion) and insomnia are rooted in a Heart and Spleen deficiency, Gui Pi Tang offers an excellent regulatory effect.
  • Mental Clarity and Rest: It deeply nourishes the mind and spirit, which helps to significantly improve sleep quality. It is also highly effective at relieving associated symptoms like dizziness, chronic fatigue, and memory loss caused by this burnout.

4. Hematological System Diseases

  • This formula is widely used for blood-related issues, such as thrombocytopenic purpura (easy bruising/bleeding) or iron-deficiency anemia, particularly when these are caused by the Spleen's inability to keep blood within the vessels.
  • Restoring Balance: Gui Pi Tang works by strengthening Spleen Qi to control bleeding while simultaneously nourishing the body to create fresh blood, helping the hematological system recover its normal function.
Gui Pi Tang

5. Digestive System Diseases

  • Patients suffering from chronic gastritis or peptic ulcers can benefit greatly if they exhibit signs of Heart and Spleen deficiency.
  • Digestive Support: If you are experiencing symptoms like a dull, lingering stomach ache, poor appetite, and severe exhaustion, Gui Pi Tang steps in to regulate the Spleen and Stomach. It promotes better digestion and nutrient absorption, which in turn boosts the body's overall immunity and aids in a faster recovery.

Herb Composition (Sovereign / Minister / Assistant / Envoy)

1. Chief Herbs: Bai Zhu, Fu Shen, and Huang Qi

  • Bai Zhu: This herb is warm, sweet, and bitter, targeting the Spleen and Stomach meridians. It is a crucial herb for strengthening the Spleen and boosting Qi, as well as drying dampness. By improving your digestive system's ability to process and absorb nutrients, it lays down a solid foundation for your body to create new Qi and blood.
  • Fu Shen: Neutral and sweet, this herb works on the Heart and Spleen. Its main job is to calm the mind and soothe the spirit, assisting the other Chief herbs in relieving the restlessness caused by a deficiency in both the Heart and Spleen.
  • Huang Qi: Slightly warm and sweet, this powerful herb enters the Spleen and Lung meridians. It is famous for its strong ability to boost Qi and lift your body's energy. It can secure your body's exterior (to stop sweating), reduce swelling, and promote healing. In the Gui Pi Tang formula, it plays a critical role by deeply tonifying the Spleen and Stomach Qi, which drives the continuous production and circulation of blood.

2. Deputy Herbs: Long Yan Rou, Suan Zao Ren, and Ren Shen

  • Long Yan Rou: Warm and sweet, this herb provides deep nourishment to the Heart and Spleen. It acts to build blood and powerfully calm the nervous system.
  • Suan Zao Ren: This sweet and sour herb targets the Heart, Liver, and Gallbladder. It excels at nourishing the Heart and Liver to calm the spirit, generate fluids, and stop excessive sweating. When teamed up with herbs like Ren Shen and Long Yan Rou, it is highly effective at treating insomnia and palpitations rooted in a Heart and Spleen deficiency.
  • Ren Shen: Slightly warm, sweet, and slightly bitter, this famous herb strongly replenishes your body's foundational "primal Qi." It boosts the Spleen and Lungs, generates fluids, and sharpens the mind, significantly enhancing the overall tonifying power of the entire formula.

3. Assistant Herbs: Mu Xiang and Zhi Gan Cao

  • Mu Xiang: Warm, acrid, and bitter, this herb is an excellent digestive aid. Because this formula is packed with rich, heavy tonics, Mu Xiang is added to keep Qi moving smoothly and prevent bloating. It ensures the medicine is "tonifying without stagnating," allowing your Qi and blood to flow without blockage.
  • Zhi Gan Cao: This neutral, sweet herb (honey-fried licorice) harmonizes the Spleen and Stomach while boosting Qi. It acts as a peacemaker, blending all the different ingredients together harmoniously while amplifying their overall tonifying effects.
Gui Pi Tang

4. Envoy Herb: Dang Gui

  • Dang Gui: Warm, sweet, and acrid, this herb targets the Liver, Heart, and Spleen meridians. It is a master at both tonifying and invigorating the blood. In this formula, it ensures that your newly generated Qi and blood are not just abundant, but also circulating smoothly. It acts as a guide, directing the medicinal effects exactly where they need to go, while providing extra nourishment to the Heart and Spleen.

Clinical Presentation in TCM

1. Pathomechanism

  • The core issue that Gui Pi Tang targets is a deficiency of both the Heart and Spleen. This often happens due to chronic overthinking, extreme stress, or poor eating habits that exhaust the digestive system.
  • Because of this burnout, the body fails to produce enough fresh Qi and blood, leaving the Heart starved of nourishment.
  • Spleen Weakness: When Spleen Qi is weak and digestion is sluggish, it leads to symptoms like a poor appetite, abdominal bloating, and loose stools.
  • Heart Blood Deficiency: When the Heart lacks sufficient blood, the mind becomes unsettled, triggering anxious symptoms like palpitations, insomnia, and vivid, exhausting dreams.

2. Efficacy

  • Gui Pi Tang is highly effective at boosting Qi, building blood, strengthening the Spleen, and nourishing the Heart.
  • It works by deeply tonifying the Spleen and Stomach's energy, which kickstarts your body's natural ability to produce abundant Qi and blood.
  • At the same time, it actively soothes and feeds the mind. By ensuring the Heart is well-nourished and energy levels are restored, it effectively resolves the complex web of symptoms caused by this dual deficiency.
Gui Pi Tang

3. Clinical Indications

  • This formula is the go-to treatment for Heart and Spleen deficiency syndrome.
  • Common Physical and Mental Signs: It is used when a patient experiences severe palpitations, forgetfulness, insomnia, night sweats, feelings of "empty heat," poor appetite, chronic fatigue, a sallow or pale complexion, a pale tongue with a thin white coating, and a thin, weak pulse.
  • Bleeding Disorders (Spleen Failing to Control Blood): It is also widely used for conditions where weak Spleen Qi can no longer hold blood within the vessels. This manifests as blood in the stool, easy bruising under the skin, or gynecological issues like heavy uterine bleeding, early periods, or excessive, pale menstrual flow.

The Mechanism in Classical Theory

1. Tonifying Both Qi and Blood

  • Powering Up Qi: Herbs like Huang Qi, Ren Shen, Bai Zhu, and Zhi Gan Cao strongly boost the Qi (energy) of the Spleen and Lungs. This creates a strong foundation, acting as the source for your body to generate new energy and blood.
  • Building Blood: At the same time, Long Yan Rou and Dang Gui step in to actively nourish and rebuild your blood supply.
  • The Synergy: By working together, they provide a powerful dual boost to both Qi and blood, ensuring that your Heart and Spleen get exactly what they need to maintain normal physiological functions and relieve the uncomfortable symptoms caused by deficiency.

2. Treating the Heart and Spleen Together

  • Calming the Mind: Herbs like Fu Shen and Suan Zao Ren are included specifically to calm the spirit and soothe a Heart that has been starved of nourishment.
  • Supporting Digestion: Meanwhile, herbs like Bai Zhu and Mu Xiang work on regulating the Spleen and Stomach. By strengthening digestion, they help the body naturally produce more Qi and blood.
  • The Mind-Body Connection: In TCM, the Heart governs the mind and spirit, while the Spleen controls digestion and nutrient absorption. By treating both simultaneously, this formula ensures that your energy flows harmoniously, leaving you mentally vibrant and physically energized.
Gui Pi Tang

3. Tonifying Without Causing Stagnation

  • Keeping Things Moving: Tonifying (nourishing) herbs can sometimes be heavy, rich, or cloying, which might slow down your digestion. The addition of Mu Xiang is a strategic move because it promotes the smooth flow of Qi.
  • Preventing Bloating: It prevents the rich, nourishing herbs from causing bloating or stagnation in the stomach. This ensures that the Spleen's digestive function remains strong, allowing the newly generated Qi and blood to be produced and circulated smoothly throughout the body.

Clinical Comparison Table

Compare Gui Pi TangBu Zhong Yi Qi TangBa Zhen TangRen Shen Yang Rong Tang
Primary Function Tonify Qi and Blood, strengthen Spleen, nourish the HeartTonify Middle Qi, raise Yang, lift the sunkenTonify Qi and BloodTonify Qi and Blood, nourish the Heart, calm the spirit
Formula Category Qi-Tonifying FormulasQi-Tonifying FormulasQi-Tonifying FormulasQi-Tonifying Formulas
Typical TCM Pattern Qi DeficiencySpleen Qi DeficiencyQi DeficiencyQi Deficiency
Main Conditions Insomnia, Fatigue & Low Energy, Poor Appetite, Anxiety Restlessness, Irregular MenstruationFatigue & Low Energy, Spontaneous Sweating, Poor Appetite, Diarrhea, General Lethargy, Susceptible to Colds, Spleen Qi DeficiencyFatigue & Low Energy, Poor Appetite, Irregular Menstruation, Dull Complexion, General Lethargy, Blood Deficiency Constitution, Qi Deficiency ConstitutionFatigue & Low Energy, Poor Appetite, Insomnia, Anxiety Restlessness, Dull Complexion
Main Herbs Ginseng Root · Astragalus Root · White Atractylodes Rhizome · Poria / Hoelen · Sour Jujube Seed · Longan Aril · Aucklandia / Costus Root · Chinese Angelica Root · Polygala Root · Honey-fried LicoriceAstragalus Root · Ginseng Root · White Atractylodes Rhizome · Chinese Angelica Root · Tangerine Peel · Cimicifuga Rhizome · Bupleurum Root · Honey-fried LicoriceGinseng Root · White Atractylodes Rhizome · Poria / Hoelen · Honey-fried Licorice · Prepared Rehmannia Root · Chinese Angelica Root · White Peony Root · Chuanxiong RhizomeGinseng Root · White Atractylodes Rhizome · Astragalus Root · Chinese Angelica Root · White Peony Root · Prepared Rehmannia Root · Tangerine Peel · Poria / Hoelen · Schisandra Fruit · Polygala Root · Honey-fried Licorice · Cinnamon Bark
Classical Source Ji Sheng Fang (Yan Yonghe, Song dynasty)Pi Wei Lun / Nei Wai Shang Bian Huo Lun (Li Dongyuan, Jin dynasty, ~1247–1249)Zheng Ti Lei Yao (Xue Ji, Ming dynasty) / derived from Si Jun Zi Tang + Si Wu TangTai Ping Hui Min He Ji Ju Fang (Song dynasty)

How to tell them apart

Gui Pi Tang tonifies Spleen-Heart for overthinking deficiency. Bu Zhong Yi Qi Tang raises Middle Qi. Ba Zhen Tang is a general dual tonic. Ren Shen Yang Rong Tang more broadly tonifies and calms.

For educational reference only, based on traditional pattern differentiation — not a substitute for professional advice.

Clinical Modifications for Gui Pi Tang

1. For Severe Palpitations

  • If your palpitations are intense, we can add Long Gu and Mu Li.
  • These herbs provide a "heavy" anchoring effect that strongly calms the spirit and settles a racing heart, offering excellent relief for more severe symptoms.

2. For Severe Insomnia

  • For patients struggling to get a good night's rest, we add Ye Jiao Teng and He Huan Pi.
  • These ingredients greatly enhance the formula's ability to nourish the Heart and relax the mind, helping you fall asleep faster and improving your overall sleep quality.

3. For Severe Blood Deficiency

  • If signs of blood deficiency are especially prominent (such as extreme paleness, dizziness, or numbness), we can increase the dosage of Dang Gui and add Shu Di Huang.
  • This gives the formula an extra power boost to rapidly build and nourish your blood supply.

4. For Spleen Deficiency with Loose Stools

  • When Spleen weakness mainly shows up as poor digestion and loose stools, we rely heavily on a larger dose of Bai Zhu, and add herbs like Shan Yao and Yi Yi Ren.
  • These are fantastic for strengthening the Spleen's digestive power and effectively stopping diarrhea.
Gui Pi Tang

5. For Concurrent Yin Deficiency

  • If you also show signs of Yin deficiency (like a dry mouth, night sweats, or a feeling of internal heat), we mix in Yin-nourishing herbs such as Mai Dong, Yu Zhu, and Sheng Di.
  • This ensures that the warming and tonifying nature of the base formula doesn't overheat your system or dry you out.

What the Science Suggests

1. Pharmacological Effects

Modern research has uncovered some fascinating ways that Gui Pi Tang works within the body:

  • Immune System Boost: It helps regulate immune function, giving your body's natural resistance and overall immunity a significant upgrade.
  • Cardiovascular Health: It improves cardiovascular performance by reducing the heart's oxygen consumption and increasing blood flow through the coronary arteries.
  • Nervous System & Mental Health: It actively regulates the release of neurotransmitters, which explains why it's so effective at improving sleep quality and your overall mental state.
  • Digestive Support: It has a highly positive impact on your gut by promoting healthy gastrointestinal motility and boosting your body's ability to digest and absorb nutrients.
Gui Pi Tang

2. Clinical Efficacy Validation

Extensive clinical studies have strongly backed up the traditional uses of Gui Pi Tang, showing it to be a highly safe and reliable option:

  • Proven Symptom Relief: It is highly effective for treating diseases related to Heart and Spleen deficiency. It shows remarkable results in clearing up classic symptoms like palpitations, insomnia, poor appetite, and a pale or sallow complexion.
  • Chronic Disease Management: It has shown a clear therapeutic edge when treating tricky modern conditions like chronic fatigue syndrome and functional dyspepsia (chronic indigestion).
  • Future Potential: As modern medical research continues to dive deeper into this formula, its applications are only expected to grow, offering broad and exciting prospects for its use in everyday modern healthcare.

Safety Considerations

1. Dietary and Lifestyle Precautions

While taking Gui Pi Tang, keep a light diet and avoid spicy, greasy, raw, cold, or irritating foods, as they may impair spleen-stomach transformation and transportation. Maintain emotional calm, avoid excessive worry and fatigue, and ensure adequate sleep to support the formula’s therapeutic effect.

2. Contraindications and Allergy Warning

Gui Pi Tang is contraindicated in patients with excess or heat patterns, such as phlegm-dampness, blood stasis, fever, bitter taste in the mouth, or dry throat, as it may worsen the condition. Do not use this formula if allergic to any of its ingredients.

Questions About Gui Pi Tang

Q1: What are the actions of Gui Pi Tang?
Gui Pi Tang has the actions of tonifying Spleen Qi, nourishing Heart Blood, calming the Shen (spirit), and restoring the Spleen’s ability to hold Blood within the vessels. It is the classic formula for combined Heart and Spleen deficiency caused by overthinking and worry.
Q2: Which modern diseases is Gui Pi Tang suited to?
Modern TCM clinical practice commonly applies it to individuals whose pattern differentiation falls within Heart-Spleen Qi and Blood deficiency, including insomnia and anxiety of this type, anemia, functional uterine bleeding or menorrhagia with pale blood, neurasthenia or chronic fatigue with poor memory and appetite, easy bruising or certain thrombocytopenic presentations, and post-stress or post-illness recovery with these signs.
Q3: Is Gui Pi Tang suitable for improving fatigue, poor appetite, palpitations, insomnia, and forgetfulness from overthinking?
For presentations of mental and physical fatigue, reduced appetite, pale or sallow complexion, palpitations, difficulty sleeping or dream-disturbed sleep, poor memory or concentration after prolonged worry or mental strain, and a pale tongue with thin white coating and thin weak pulse — in those whose pattern differentiation confirms Heart and Spleen Qi-Blood deficiency — TCM commonly applies Gui Pi Tang as an adjunct. It cannot replace standard medical treatment.
Q4: Who should not take Gui Pi Tang?
Those with excess Heat, Yin-deficiency Heat, active exterior patterns (fever or acute infection), or significant Damp-Heat accumulation are generally not suitable. The formula is warming and tonifying; it can aggravate Heat or trap an exterior pathogen. Use should be assessed by a qualified TCM physician.
Q5: Why does this formula address both the Spleen and the Heart?
Excessive thinking and worry injure the Spleen, weakening its ability to transform Qi and Blood and to hold Blood in the vessels. The resulting Blood deficiency fails to nourish the Heart, leading to palpitations, insomnia, and restless Shen. By tonifying Spleen Qi (the source of Blood) and directly nourishing Heart Blood while calming the spirit, Gui Pi Tang restores both organs and the mental-emotional balance that depends on them.
Q6: Can Gui Pi Tang help with bleeding caused by Spleen Qi deficiency (Spleen not controlling Blood)?
Yes. One of its classical indications is bleeding due to the Spleen’s failure to hold Blood — such as pale, prolonged, or early menstrual bleeding, easy bruising, or blood in the stool — when accompanied by the Qi and Blood deficiency signs. The Qi-tonifying herbs help restore the Spleen’s containing function while Blood-nourishing herbs replenish what has been lost.
Q7: What are the main ingredients of Gui Pi Tang?
Key herbs include Ren Shen (or Dang Shen) and Huang Qi to strongly tonify Qi; Bai Zhu and Fu Ling (or Fu Shen) to strengthen the Spleen; Dang Gui and Long Yan Rou to nourish Blood and calm the Shen; Suan Zao Ren and Yuan Zhi to nourish the Heart and calm the spirit; Mu Xiang to move Qi and prevent stagnation from the tonics; and Zhi Gan Cao, often with Sheng Jiang and Da Zao, to harmonize.
Q8: Is Gui Pi Tang suitable for long-term use?
It may be used for a course of weeks to months in chronic Heart-Spleen deficiency under professional supervision, as rebuilding Qi and Blood takes time. Digestion and overall response should be monitored; if Heat signs or stagnation appear, the formula may need adjustment.
Q9: How does Gui Pi Tang differ from pure Qi tonics or pure Blood tonics?
Pure Qi tonics strengthen Spleen Qi but do not specifically nourish Heart Blood or calm the Shen. Pure Blood tonics replenish Blood but may not restore the Spleen’s generating and holding functions. Gui Pi Tang uniquely combines Spleen Qi tonification, Heart Blood nourishment, and spirit-calming actions, making it ideal for the overthinking, fatigue-plus-insomnia-plus-bleeding pattern.
Q10: What lifestyle advice supports the use of Gui Pi Tang?
Reducing excessive mental work and worry, establishing regular meals and sleep, eating warm and easily digestible foods, gentle rather than exhausting activity, and allowing adequate rest help the formula rebuild Spleen Qi and Heart Blood. Persistent fatigue, bleeding, or sleep problems should be properly evaluated by a healthcare professional.

General Questions

How do I choose the right formula?
TCM formulas are traditionally selected according to individual pattern differentiation rather than by symptom alone. If you're not sure which formula fits your presentation, take our AI Assessment below for a personalized starting point, then confirm with a qualified TCM practitioner.
What are concentrated herbal granules?
Concentrated herbal granules are made by decocting raw herbs, then extracting and concentrating the resulting liquid into a fine granule or powder form. This preserves the same active compounds as a traditional decoction while making the herbs far easier to store, measure, and prepare.
How should I take these products?
Dissolve the recommended amount of granules in hot water, stir until fully dissolved, and drink while warm — following the dosage and frequency advised by your TCM practitioner or as stated on the product packaging.
Are concentrated herbal granules equivalent to traditional decoctions?
Concentrated granules are produced from the same herbs and processed to retain their active compounds, so they are traditionally regarded as a convenient alternative to decoctions rather than a different remedy. Some practitioners note subtle differences in strength or absorption between the two forms, so your TCM practitioner may adjust dosage accordingly.
Are your products authentic?
Yes. HJMEDICAL sources its concentrated granules exclusively from established, reputable manufacturers such as Nong's and Hoi Tin, both long-standing names in the TCM granules industry, with GMP compliance stated directly on their packaging.
Are HJMEDICAL products manufactured under GMP standards?
HJMEDICAL sources its concentrated granules from established, reputable manufacturers such as Nong's and Hoi Tin, both long-standing names in the TCM granules industry. GMP compliance for these products is stated directly on their packaging.
Do you ship internationally?
Yes — we ship worldwide! Every order goes out via Hong Kong Post, and your exact shipping cost and estimated delivery time for your address are calculated and shown right at checkout, so there are never any surprises. We also offer free shipping once your order reaches our free-shipping threshold, so it's easy to stock up on your favorite formulas and save.
Can I take more than one formula at the same time?
Some formulas are traditionally combined, while others overlap or counteract each other. We recommend checking with a qualified TCM practitioner before combining formulas, especially if you are already taking other medication.
Are these products suitable during pregnancy or breastfeeding?
Some TCM formulas are not suitable during pregnancy or breastfeeding. Please consult a qualified TCM practitioner or your doctor before use if you are pregnant, trying to conceive, or nursing.
Do these products replace medical treatment?
No. These products are traditional herbal supplements intended to support wellbeing according to TCM principles — they are not a replacement for professional medical diagnosis or treatment. Please consult a qualified TCM practitioner or licensed healthcare provider before starting, stopping, or combining any treatment, especially if you have a chronic condition.
Medical Disclaimer

For general TCM education only — not medical advice. Consult a qualified TCM practitioner or licensed healthcare provider before use, especially if pregnant, nursing, on medication, or managing a chronic condition.

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Gui Pi Tang: Classic TCM Formula for Spleen Qi & Heart Blood Deficiency, Fatigue & Insomnia