Calm the Shen Formulas

桂枝加龙骨牡蛎汤 · Guì Zhī Jiā Lóng Gǔ Mǔ Lì Tāng

Gui Zhi Jia Long Gu Mu Li Tang

A Jin Gui formula based on Gui Zhi Tang with Long Gu and Mu Li, for Yin-Yang disharmony with loss of essence, dream emission, insomnia and a floating deficient pulse.

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Last reviewed August 2026
Formula CategoryCalm the Shen Formulas
Primary PatternYang Deficiency
Primary FunctionHarmonise Yin and Yang, secure essence, calm the spirit
Primary Therapeutic PrincipleRegulate Yin-Yang, astringe essence and calm the Shen
Main HerbsCinnamon Twig · White Peony Root · Fresh Ginger · Jujube / Chinese Date · Honey-fried Licorice · Dragon Bone / Fossilized Bone · Oyster Shell
Classical SourceJin Gui Yao Lue (Zhang Zhongjing, Eastern Han)

Why This Formula?

Traditionally selected for Yin-Yang disharmony with insomnia, seminal loss or sweating from insecurity of essence — a harmonising and astringing formula rather than a pure heat-clearing or pure Yang-tonifying one.

Traditionally selected for Yin-Yang disharmony with insomnia, seminal loss or sweating from insecurity of essence — a harmonising and astringing formula rather than a pure heat-clearing or pure Yang-tonifying one.

What Is Gui Zhi Jia Long Gu Mu Li Tang?

1. Classical Literature

Gui Zhi Jia Long Gu Mu Li Tang (桂枝加龙骨牡蛎汤), or Cinnamon Twig Decoction plus Dragon Bone and Oyster Shell, is a classical formula from Zhang Zhongjing’s Jin Gui Yao Lue (Essential Prescriptions from the Golden Cabinet). It belongs to the category of formulas that harmonize Yin and Yang and calm the spirit.

This formula addresses deficiency of both Yin and Yang with floating Yang and restless spirit, often seen in consumptive patterns. Typical signs include seminal emission or nocturnal emission in men, dream-disturbed sleep or dream intercourse in women, palpitations, insomnia, spontaneous sweating or night sweats, lower abdominal tension or cold sensation, dizziness, a pale tongue, and a hollow or deficient pulse.

Building on the foundation of Gui Zhi Tang to harmonize Ying and Wei while gently supporting Yin and Yang, the addition of Long Gu and Mu Li anchors floating Yang, calms the spirit, and astringes Essence to stop leakage, restoring balance between the Heart and Kidneys.

Gui Zhi Jia Long Gu Mu Li Tang: Harmonising Ying-Wei, Astringing Essence and Calming the Spirit | HJMEDICAL

2. Male Disorders

  • Spermatorrhea and Premature Ejaculation

    • Pattern: Kidney deficiency with failure to secure essence and yin–yang disharmony.
    • Use: Gui Zhi Jia Long Gu Mu Li Tang to harmonize yin and yang and consolidate Kidney essence.
    • Typical features: lumbar and knee soreness/weakness, dizziness, tinnitus, aversion to cold.
    • Expected response: reduced frequency of spermatorrhea and premature ejaculation; alleviation of Kidney‑deficiency signs over time.
  • Male Infertility

    • Pattern: Yin–yang disharmony with depletion of Kidney essence affecting semen quality.
    • Use: Gui Zhi Jia Long Gu Mu Li Tang to rebalance yin–yang and nourish/secure essence.
    • Presentation: reduced sexual function, abnormal semen parameters.
    • Expected response: gradual improvement in semen quality and quantity, with a corresponding rise in the likelihood of conception.

3. Gynaecological Disorders

  • Menstrual Irregularities

    • Pattern: Irregular cycles, abnormal flow, dysmenorrhea due to ying–wei and yin–yang disharmony.
    • Mechanism: Harmonizes ying and wei, promotes smooth qi–blood, regulates the cycle, and eases pain.
    • Example: delayed menses with scant flow plus aversion to cold and spontaneous sweating (ying–wei disharmony) may normalize after treatment.
  • Menopausal Syndrome

    • Features: hot flushes, night sweating, insomnia, mood lability linked to yin–yang imbalance.
    • Use: Gui Zhi Jia Long Gu Mu Li Tang to harmonize yin–yang, calm the spirit, and settle the will.
    • Expected benefits: reduced vasomotor symptoms, improved sleep quality, steadier mood, smoother transition through menopause.
Gui Zhi Jia Long Gu Mu Li Tang: Harmonising Ying-Wei, Astringing Essence and Calming the Spirit | HJMEDICAL

4. Psychiatric and Neurological Disorders

  • Insomnia

    • Indications: insomnia from emotional disturbance, yin–yang mismatch, or qi–blood disharmony.
    • Mechanism: Rebalances yin–yang and calms the spirit (shen).
    • Outcomes: easier sleep onset, fewer nocturnal awakenings and dreams, longer sleep duration, improved daytime mental state.
  • Anxiety and Depression

    • Role: Adjunct formula for emotional instability, insomnia, palpitations associated with yin–yang disharmony and unsettled shen.
    • Effects: eases anxiety and depressive affect, improves sleep and palpitations, and enhances quality of life by restoring internal balance.

Herb Composition (Sovereign / Minister / Assistant / Envoy)

1. Chief Herb — Gui Zhi (Cinnamon Twig)

  • Flavour, Nature, Channel Tropism
    • Acrid, sweet; warm. Enters Heart, Lung, Bladder.
  • Actions
    • Induces mild sweating to release the muscles and exterior; warms and unblocks the channels; assists yang to transform qi.
    • Disperses external wind‑cold; warms the channels to move qi and blood for cold‑induced pain from congealing and stasis.
    • Assists bladder qi transformation to promote fluid metabolism.
    • In Gui Zhi Jia Long Gu Mu Li Tang, Gui Zhi leads as the chief to release the exterior and harmonize ying and wei, laying the foundation for treating externally contracted wind‑cold with ying–wei disharmony.

2. Deputy Herb — Shao Yao (Peony Root)

  • Flavour, Nature, Channel Tropism
    • Bitter, sour; slightly cold. Enters Liver, Spleen.
  • Actions
    • Nourishes blood, regulates menstruation; astringes yin, stops sweating; softens the Liver, relieves pain; calms Liver yang.
    • Pairs with Gui Zhi as complementary opposites—one dispersing, one astringing—so muscles are released without over‑dispersing and without excessive sweating that harms fluids.
    • Nourishes blood and harmonizes the ying to help bring ying and wei into balance; eases spontaneous/night sweating from ying–wei disharmony and relieves cramping or abdominal pain.

3. Assistant Herbs — Sheng Jiang (Fresh Ginger) and Da Zao (Jujube)

  • Sheng Jiang (Fresh Ginger)

    • Flavour, Nature, Channel Tropism: Acrid; slightly warm. Enters Lung, Spleen, Stomach.
    • Actions: Releases the exterior, disperses cold; warms the middle to stop vomiting; transforms phlegm to relieve cough.
    • Role: Supports Gui Zhi in dispersing wind‑cold, strengthens exterior‑releasing effect, and protects the Stomach to aid absorption and overall efficacy.
  • Da Zao (Jujube)

    • Flavour, Nature, Channel Tropism: Sweet; warm. Enters Spleen, Stomach, Heart.
    • Actions: Tonifies the middle and boosts qi; nourishes blood and calms the spirit.
    • Role: With Sheng Jiang, harmonizes Spleen/Stomach and strengthens transform/transport so qi and blood have a solid source; assists Shao Yao in nourishing blood and moderates the formula to make it gentler and easier to take.
Gui Zhi Jia Long Gu Mu Li Tang: Harmonising Ying-Wei, Astringing Essence and Calming the Spirit | HJMEDICAL

4. Envoy Herbs — Long Gu (Dragon Bone) and Mu Li (Oyster Shell)

  • Long Gu (Dragon Bone)

    • Flavour, Nature, Channel Tropism: Sweet, astringent; neutral. Enters Heart, Liver, Kidney.
    • Actions: Settles fright and calms the spirit; calms the Liver and subdues yang; astringes and consolidates.
    • Role: Heavily anchors the spirit—useful for insomnia, vivid dreaming, palpitations with fright from yin–yang disharmony. Also astringes to help spontaneous/night sweating and supports overall balance.
  • Mu Li (Oyster Shell)

    • Flavour, Nature, Channel Tropism: Salty; slightly cold. Enters Liver, Gallbladder, Kidney.
    • Actions: Heavily settles and calms the spirit; subdues yang and nourishes yin; softens hardness and dissipates binds.
    • Role: Works with Long Gu to stabilize the spirit and will; helps rebalance yin and yang, especially when yin is deficient with yang hyperactivity. In Gui Zhi Jia Long Gu Mu Li Tang, Long Gu and Mu Li serve as envoy herbs to anchor and calm, astringe and consolidate, and restore yin–yang harmony—addressing the core pathomechanism treated by this formula.

Clinical Presentation in TCM

1. Pathomechanism Analysis

  • Yin–Yang Disharmony

    • Target pattern: a mismatch between yin and yang.
    • Triggers:
      • After externally contracted wind‑cold → ying–wei disharmony.
      • Internal depletion: yin deficiency failing to anchor yang, or yang deficiency failing to secure yin.
    • Typical scenarios:
      • Yin‑fluid depletion from overwork or emotional strain → relatively hyperactive yang → vexing restlessness, insomnia, tidal fever, night sweating.
      • Prolonged illness with weak yang qi → failure to secure yin fluids → spontaneous sweating, aversion to cold.
  • Qi–Blood Disharmony

    • Ying–wei disharmony disrupts qi–blood flow and zang–fu function.
    • Wind‑cold at the exterior:
      • Wei qi can’t warm/protect the surface; ying qi fails to be contained → fever, chills, sweating abnormalities.
    • Ongoing yin–yang imbalance impairs qi–blood generation and movement → insufficiency or stasis.
    • Emotional constraint can cause qi stagnation and blood stasis, which then worsens yin–yang disharmony in a vicious cycle.

2. Actions

  • Harmonising Yin and Yang

    • Gui Zhi + Shao Yao regulate ying–wei to rebalance yin–yang.
    • Long Gu + Mu Li anchor and calm, subdue hyperactive yang, and help restore yin–yang equilibrium.
    • Useful for spontaneous/night sweating, insomnia, and vivid dreaming linked to yin–yang mismatch.
  • Consolidating and Stopping Perspiration

    • Long Gu + Mu Li astringe and secure: effective for spontaneous sweating (yang deficiency, insecure exterior) and night sweating (yin deficiency with internal heat).
    • Outcome: reduces excessive sweating, improves comfort and daily function.
  • Calming the Spirit and Settling the Will

    • Long Gu + Mu Li heavily settle shen for insomnia and palpitation with fright due to yin–yang disharmony.
    • Gui Zhi + Shao Yao harmonise ying–wei, which further steadies the mind.
    • Net effect: better sleep, fewer dreams, reduced anxiety and tension.
Gui Zhi Jia Long Gu Mu Li Tang: Harmonising Ying-Wei, Astringing Essence and Calming the Spirit | HJMEDICAL

3. Indications

  • Deficiency‑Taxation with Loss of Essence

    • Signs:
      • In men: spermatorrhea, seminal leakage.
      • In women: nocturnal emission‑like presentations with dream intercourse.
      • Often with dull complexion, aversion to cold, dizziness, insomnia, profuse dreaming.
    • Mechanism: yin–yang disharmony with Kidney failure to secure essence.
    • Formula goal: harmonise yin–yang and consolidate essence.
  • Spontaneous Sweating and Night Sweating from Yin–Yang Disharmony

    • Spontaneous sweating: mainly yang deficiency failing to secure the exterior.
    • Night sweating: mainly yin deficiency with internal heat.
    • Formula rebalances yin–yang so yang secures and yin is retained → sweating decreases; fatigue, shortness of breath, and vexing heat also improve.
  • Insomnia, Profuse Dreaming, Palpitations with Fright

    • Features: trouble falling/staying asleep, many dreams, frequent waking, palpitations, sense of fright.
    • Mechanism: yin–yang mismatch with unsettled shen.
    • Formula calms the spirit and restores yin–yang harmony, improving sleep quality and mental steadiness.

The Mechanism in Classical Theory

1. The Gui Zhi–Shao Yao Combination

  • Harmonising Ying and Wei

    • Gui Zhi is acrid‑warm and releases the muscles/exterior, dispersing wind‑cold so the pathogen can be vented.
    • Shao Yao is sour‑cool, astringes yin, and harmonises the ying, curbing over‑dispersal from Gui Zhi and preventing sweat‑induced fluid loss.
    • One disperses, one astringes—together they harmonise ying and wei, restore smooth qi‑blood flow, and normalise zang‑fu function, easing fever, chills, and abnormal sweating due to ying–wei disharmony.
  • Balancing Yin and Yang

    • Gui Zhi warms and assists yang; Shao Yao slightly cools and nourishes yin.
    • Their pairing rebalances excess/deficiency of yin and yang:
      • Yang deficiency with yin excess: Gui Zhi boosts yang while Shao Yao restrains yin‑cold.
      • Yin deficiency with yang hyperactivity: Shao Yao nourishes yin while Gui Zhi prevents over‑dispersal of yang.
    • Net effect: restores relative yin–yang balance.

2. The Role of Sheng Jiang and Da Zao

  • Harmonising the Spleen and Stomach

    • Sheng Jiang (acrid‑warm) warms the Stomach, disperses cold, and supports Spleen/Stomach transform‑transport.
    • Da Zao (sweet‑warm) tonifies the Spleen and boosts qi.
    • Together they harmonise the middle, strengthen postnatal qi‑blood generation, improve herb absorption, and bolster resistance—so Gui Zhi Jia Long Gu Mu Li Tang works more effectively.
  • Reinforcing Medicinal Potency

    • Sheng Jiang assists Gui Zhi in dispersing wind‑cold.
    • Da Zao supports Shao Yao in nourishing blood and harmonising the ying.
    • Synergy: enhances exterior‑releasing, ying‑harmonising, and shen‑calming actions, making the overall effect more comprehensive and coordinated.
Gui Zhi Jia Long Gu Mu Li Tang: Harmonising Ying-Wei, Astringing Essence and Calming the Spirit | HJMEDICAL

3. The Significance of Long Gu and Mu Li

  • Heavy Settling to Calm the Spirit

    • Long Gu and Mu Li anchor and calm the shen when yin–yang disharmony causes restlessness—helping insomnia, vivid dreams, and palpitations with fright.
    • By stabilising the spirit, mental tranquility improves and recovery is supported.
  • Astringing and Consolidating

    • Their astringent, consolidating action helps spontaneous/night sweating, spermatorrhea, and seminal leakage.
    • In deficiency‑taxation with loss of essence and sweat disorders, they secure fluids and essence, curb leakage of righteous qi, and promote recovery.
  • Calming the Liver and Subduing Yang

    • Both calm the Liver and subdue hyperactive yang, useful when yin deficiency leads to yang rising.
    • They ease dizziness/vertigo from yang hyperactivity and help re‑establish yin–yang balance for normal physiology.

Clinical Comparison Table

Compare Gui Zhi Jia Long Gu Mu Li TangChai Hu Jia Long Gu Mu Li TangSuan Zao Ren TangJin Gui Shen Qi Wan
Primary Function Harmonise Yin and Yang, secure essence, calm the spiritHarmonise Shaoyang, calm the spirit, relieve constraintNourish Blood, calm the spirit, clear heatWarm and tonify Kidney Yang
Formula Category Calm the Shen FormulasCalm the Shen FormulasCalm the Shen FormulasYang-Tonifying Formulas
Typical TCM Pattern Yang DeficiencyQi StagnationBlood DeficiencyKidney Yang Deficiency
Main Conditions Insomnia, Anxiety Restlessness, Spontaneous Sweating, Premature Ejaculation, Low LibidoAnxiety Restlessness, Insomnia, Chest Tightness, Emotional DepressionInsomnia, Anxiety Restlessness, Dry Mouth & Throat, Night SweatsFrequent Nocturia, Edema, Cold Limbs, Low Libido, Fatigue & Low Energy, Frequent Urination
Main Herbs Cinnamon Twig · White Peony Root · Fresh Ginger · Jujube / Chinese Date · Honey-fried Licorice · Dragon Bone / Fossilized Bone · Oyster ShellBupleurum Root · Dragon Bone / Fossilized Bone · Oyster Shell · Scutellaria / Baikal Skullcap · Ginseng Root · Cinnamon Twig · Poria / Hoelen · Pinellia Rhizome · Rhubarb Root and Rhizome · Fresh Ginger · Jujube / Chinese DateSour Jujube Seed · Poria / Hoelen · Anemarrhena Rhizome · Chuanxiong Rhizome · Licorice RootPrepared Rehmannia Root · Cornus Fruit · Chinese Yam · Poria / Hoelen · Moutan Bark / Tree Peony Bark · Alisma Rhizome · Cinnamon Twig · Prepared Aconite Root
Classical Source Jin Gui Yao Lue (Zhang Zhongjing, Eastern Han)Shang Han Lun (Zhang Zhongjing, Eastern Han)Jin Gui Yao Lue (Zhang Zhongjing, Eastern Han)Jin Gui Yao Lue (Zhang Zhongjing, Eastern Han)

How to tell them apart

Gui Zhi Jia Long Gu Mu Li Tang harmonises and secures for deficiency with floating Yang. Chai Hu Jia Long Gu Mu Li Tang addresses constrained heat with restlessness more strongly. Suan Zao Ren Tang nourishes Blood and calms the spirit for deficiency irritability. Jin Gui Shen Qi Wan warms and tonifies Kidney Yang for deeper Yang deficiency.

For educational reference only, based on traditional pattern differentiation — not a substitute for professional advice.

Clinical Modifications for Gui Zhi Jia Long Gu Mu Li Tang

1. Pronounced Yang Deficiency

  • Add Fu Zi (Aconite)

    • Acrid‑hot; powerfully warms and restores source yang, disperses cold, relieves pain.
    • With the base formula, strengthens yang‑warming to ease aversion to cold, cold limbs, and cold lumbar/knee pain; helps reestablish yin–yang balance.
  • Add Rou Gui (Cinnamon Bark)

    • Supplements fire, assists yang, warms and unblocks the channels, disperses cold to relieve pain.
    • Suitable for milder yang deficiency; pairs with Gui Zhi to enhance warming/unblocking of yang qi, improve qi‑blood circulation, and reduce limb pain.

2. Pronounced Yin Deficiency

  • Add Sheng Di (Rehmannia Root, raw) and Mai Dong (Ophiopogon Root)

    • Sheng Di: clears heat, cools blood, nourishes yin, generates fluids.
    • Mai Dong: nourishes yin, moistens Lung, benefits Stomach, generates fluids, clears Heart vexation.
    • Synergize with Shao Yao to reinforce yin‑nourishing and heat‑clearing, easing dry mouth/throat, tidal fever, night sweating, and five‑center heat.
  • Add Gui Jia (Tortoise Plastron) and Bie Jia (Turtle Shell)

    • Nourish yin and subdue yang; heavily anchor rising yang.
    • With Long Gu and Mu Li, further calm the Liver and subdue yang, improving dizziness, vertigo, and vexing agitation from yin deficiency with yang hyperactivity; restores yin–yang balance.
Gui Zhi Jia Long Gu Mu Li Tang: Harmonising Ying-Wei, Astringing Essence and Calming the Spirit | HJMEDICAL

3. Qi‑Blood Insufficiency

  • Add Huang Qi (Astragalus Root) and Dang Shen (Codonopsis Root)
    • Huang Qi: tonifies qi, raises yang, consolidates exterior to stop sweating, promotes urination to reduce edema, generates fluids to nourish blood.
    • Dang Shen: strengthens Spleen, benefits Lung, nourishes blood, generates fluids.
    • Together, boost qi and enrich blood, correcting pallor, dizziness, fatigue, and improving overall vitality.

What the Science Suggests

Gui Zhi Jia Long Gu Mu Li Tang (Cinnamon Twig Decoction plus Dragon Bone and Oyster Shell) is a classical modification of Gui Zhi Tang in Traditional Chinese Medicine that nourishes the blood, warms heart yang, and anchors floating yang.

It effectively calms the spirit (shen), treats insomnia, palpitations, dizziness, night sweats, spontaneous sweat, and fullness in the chest arising from disharmony of liver qi and deficiency of heart yang. Key ingredients such as Gui Zhi, Bai Shao, Sheng Jiang, Da Zao, Gan Cao, Long Gu (dragon bone), and Mu Li (oyster shell) work together to harmonize the interior and exterior, restrain floating yang, and stabilize the downward movement of qi, thereby restoring peace to the heart and mind. This formula is particularly useful when liver qi disturbs the spirit and causes unstable heart yang.

1. Pharmacological Research

  • Focus areas: sedative, anxiolytic, anticonvulsant, and autonomic nervous system–regulating effects.
  • Evidence: in vitro and in vivo studies suggest Long Gu, Mu Li, and Suan Zao Ren modulate central inhibition and the GABA system.
  • Note: mechanisms remain incompletely defined and need further clarification.

2. Clinical Research

  • Main targets: insomnia, palpitations, nervous hypersensitivity, menopausal vexing heat.
  • Findings: some randomized controlled and observational studies indicate benefit.
  • Limitations: variable sample sizes, inconsistent blinding, heterogeneous outcomes.
  • Need: larger, high‑quality trials to confirm efficacy and safety for Gui Zhi Jia Long Gu Mu Li Tang.

3. Dosage Form Development

  • Forms beyond decoctions/granules: pills, capsules, oral liquids, compound preparations—to improve adherence and stability.
  • Quality control: extraction and purification of active constituents to enable standardized production and tighter batch consistency.
Gui Zhi Jia Long Gu Mu Li Tang: Harmonising Ying-Wei, Astringing Essence and Calming the Spirit | HJMEDICAL

4. Future Directions

  • Research priorities:
    • Define molecular mechanisms and pathways (e.g., GABAergic modulation, autonomic balance).
    • Conduct multi‑center, randomized controlled trials to establish indications and dose–response.
    • Advance quality standards, drug–drug interaction data, and individualized dosing guidelines.
  • Goal: improve safety, reproducibility, and real‑world therapeutic outcomes for Gui Zhi Jia Long Gu Mu Li Tang.

Safety Considerations

This formula should be used with caution or avoided by those with fever, excess heat, yin deficiency with internal heat, or severe hepatic or renal dysfunction. Caution is also warranted for those with oyster allergy or thyroid dysfunction.

Long Gu and Muli are heavy-settling, spirit-calming medicinals; patients with weak gastrointestinal function should monitor for digestive discomfort during use. For pregnant women, long-term high-dose use, or concurrent use with Western pharmaceuticals, a TCM practitioner or treating physician should be consulted beforehand.

Questions About Gui Zhi Jia Long Gu Mu Li Tang

Q1: What are the actions of Gui Zhi Jia Long Gu Mu Li Tang?
Gui Zhi Jia Long Gu Mu Li Tang has the actions of harmonizing Yin and Yang, calming the spirit, and anchoring and astringing. It is Gui Zhi Tang with the addition of Long Gu and Mu Li, used to restore balance when Yin and Yang are unstable and vital substances are leaking.
Q2: Which modern diseases is Gui Zhi Jia Long Gu Mu Li Tang suited to?
Modern TCM clinical practice commonly applies it to individuals whose pattern differentiation falls within Yin-Yang disharmony with leakage, including insomnia with vivid dreams or easy startling, palpitations and anxiety of deficiency type, seminal emission or premature ejaculation, spontaneous or night sweating, enuresis, and certain menopausal or neurasthenic presentations with the classical signs.
Q3: Is Gui Zhi Jia Long Gu Mu Li Tang suitable for improving seminal emission, lower abdominal tension, and restless sleep?
For presentations of lower abdominal string-like tension or cold sensation in the genitals, seminal emission (in men) or dreaming of intercourse (in women), dizziness, hair loss, palpitations, insomnia with excessive dreams, and a deficient, large, hollow or stirring pulse — in those whose pattern differentiation confirms deficiency taxation with Yin-Yang instability — TCM commonly applies Gui Zhi Jia Long Gu Mu Li Tang as an adjunct. It cannot replace standard medical treatment.
Q4: Who should not take Gui Zhi Jia Long Gu Mu Li Tang?
Those with Yin deficiency and vigorous Fire, excess Heat patterns, or Damp-Heat type leakage are generally not suitable. The formula contains warming Gui Zhi and is designed for deficiency with instability rather than excess Heat or pure Yin-deficient Fire. Use should be assessed by a qualified TCM physician.
Q5: Why are Long Gu and Mu Li added to Gui Zhi Tang in this formula?
Gui Zhi Tang harmonizes Ying and Wei and supports the balance of Yin and Yang. Long Gu and Mu Li are heavy, settling, and astringent; they anchor floating Yang, calm the spirit, and secure leakage of essence, sweat, and other vital substances. Together they address both the disharmony and the resulting loss of fluids and essence.
Q6: Can this formula help with both physical leakage symptoms and emotional restlessness?
Yes. When Yin and Yang are unstable, the spirit may become restless (insomnia, vivid dreams, palpitations, anxiety) while essence and fluids leak (seminal emission, sweating, enuresis). By harmonizing Yin-Yang and anchoring with Long Gu and Mu Li, the formula addresses both the mental-emotional unsettledness and the physical leakage.
Q7: What are the main ingredients of Gui Zhi Jia Long Gu Mu Li Tang?
The formula consists of the five herbs of Gui Zhi Tang — Gui Zhi, Bai Shao, Sheng Jiang, Da Zao, and Zhi Gan Cao — plus Long Gu (Dragon Bone) and Mu Li (Oyster Shell). The Gui Zhi Tang group harmonizes Ying and Wei and supports Yin-Yang balance; Long Gu and Mu Li anchor, astringe, and calm the spirit.
Q8: Is Gui Zhi Jia Long Gu Mu Li Tang suitable for long-term use?
It may be used for a course of treatment under professional supervision while the Yin-Yang instability and leakage symptoms are being addressed. Once balance is restored and leakage reduces, the formula can be adjusted or tapered. Continuous use without reassessment is not ideal.
Q9: How does this formula differ from pure astringent or pure spirit-calming formulas?
Pure astringents only stop leakage without addressing the underlying Yin-Yang disharmony. Pure spirit-calming formulas may settle the mind but not secure essence or harmonize Ying and Wei. Gui Zhi Jia Long Gu Mu Li Tang does both: it restores the foundational balance through Gui Zhi Tang while Long Gu and Mu Li anchor and astringe, making it suitable for deficiency with concurrent leakage and restlessness.
Q10: What lifestyle advice supports the use of Gui Zhi Jia Long Gu Mu Li Tang?
Adequate rest, regular sleep schedule, moderation in sexual activity when essence is leaking, avoidance of excessive stimulation or late nights, and gentle support of overall recovery help the formula restore Yin-Yang balance and secure leakage. Professional guidance remains essential for accurate pattern differentiation and safe use.

General Questions

How do I choose the right formula?
TCM formulas are traditionally selected according to individual pattern differentiation rather than by symptom alone. If you're not sure which formula fits your presentation, take our AI Assessment below for a personalized starting point, then confirm with a qualified TCM practitioner.
What are concentrated herbal granules?
Concentrated herbal granules are made by decocting raw herbs, then extracting and concentrating the resulting liquid into a fine granule or powder form. This preserves the same active compounds as a traditional decoction while making the herbs far easier to store, measure, and prepare.
How should I take these products?
Dissolve the recommended amount of granules in hot water, stir until fully dissolved, and drink while warm — following the dosage and frequency advised by your TCM practitioner or as stated on the product packaging.
Are concentrated herbal granules equivalent to traditional decoctions?
Concentrated granules are produced from the same herbs and processed to retain their active compounds, so they are traditionally regarded as a convenient alternative to decoctions rather than a different remedy. Some practitioners note subtle differences in strength or absorption between the two forms, so your TCM practitioner may adjust dosage accordingly.
Are your products authentic?
Yes. HJMEDICAL sources its concentrated granules exclusively from established, reputable manufacturers such as Nong's and Hoi Tin, both long-standing names in the TCM granules industry, with GMP compliance stated directly on their packaging.
Are HJMEDICAL products manufactured under GMP standards?
HJMEDICAL sources its concentrated granules from established, reputable manufacturers such as Nong's and Hoi Tin, both long-standing names in the TCM granules industry. GMP compliance for these products is stated directly on their packaging.
Do you ship internationally?
Yes — we ship worldwide! Every order goes out via Hong Kong Post, and your exact shipping cost and estimated delivery time for your address are calculated and shown right at checkout, so there are never any surprises. We also offer free shipping once your order reaches our free-shipping threshold, so it's easy to stock up on your favorite formulas and save.
Can I take more than one formula at the same time?
Some formulas are traditionally combined, while others overlap or counteract each other. We recommend checking with a qualified TCM practitioner before combining formulas, especially if you are already taking other medication.
Are these products suitable during pregnancy or breastfeeding?
Some TCM formulas are not suitable during pregnancy or breastfeeding. Please consult a qualified TCM practitioner or your doctor before use if you are pregnant, trying to conceive, or nursing.
Do these products replace medical treatment?
No. These products are traditional herbal supplements intended to support wellbeing according to TCM principles — they are not a replacement for professional medical diagnosis or treatment. Please consult a qualified TCM practitioner or licensed healthcare provider before starting, stopping, or combining any treatment, especially if you have a chronic condition.
Medical Disclaimer

For general TCM education only — not medical advice. Consult a qualified TCM practitioner or licensed healthcare provider before use, especially if pregnant, nursing, on medication, or managing a chronic condition.

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Gui Zhi Jia Long Gu Mu Li Tang: Classic TCM Formula for Heart Yang Deficiency, Night Sweats & Insomnia