1. Classical Literature
Sang Piao Xiao San (桑螵蛸散), or Mantis Egg-Case Powder, is a classical formula commonly cited from Chen Jiamo’s Ben Cao Meng Quan and later formula collections. It belongs to the category of formulas that stabilize the Kidney, astringe Essence, and calm the Heart.
This formula addresses deficiency of both Heart and Kidney in which Essence is not secured and the Heart spirit is unsettled. Typical signs include frequent urination or cloudy urine, nocturnal emission or spermatorrhea, forgetfulness, insomnia or dream-disturbed sleep, lower back weakness, a pale tongue, and a thin weak pulse.
Combining Sang Piao Xiao as the chief herb to tonify the Kidney and astringe Essence and urine, Long Gu and Gui Ban to stabilize, astringe, and nourish Yin, Ren Shen to tonify Qi, Dang Gui to nourish Blood, and Fu Shen, Yuan Zhi, and Shi Chang Pu to calm the spirit and restore communication between Heart and Kidney, Sang Piao Xiao San effectively secures Essence, reduces leakage, and calms the mind by treating both the Heart and the Kidney.
2. Andrological Conditions
Effectively treats frequent seminal emission or spermatorrhoea, especially when accompanied by heart-kidney non-interaction symptoms like mental fatigue, palpitations, and insomnia. It regulates, tonifies, and astringes essence, improving patient quality of life.
3. Gynaecological Conditions
Applicable for frequent urination and enuresis stemming from heart-kidney non-interaction. This includes postpartum or perimenopausal women presenting with such symptoms, where it is used based on specific pattern differentiation.

4. Other Conditions
Considered for insomnia, poor memory, and related symptoms caused by heart-kidney non-interaction, particularly when linked with seminal emission, spermatorrhoea, or frequent urination. The formula restores systemic balance, improving multiple symptoms concurrently.