Shi Liu Wei Liu Qi Yin

Classical TCM Formula Profile

Part of the HJMEDICAL TCM Discovery Center

十六味流氣飲 · Shí Liù Wèi Liú Qì Yǐn

A qi-flowing formula for stagnation with swelling and toxin.

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Quick Facts

Formula Category
Qi-Regulating Formulas
Primary Pattern
Qi Stagnation
Primary Function
Move qi, resolve toxin, reduce swelling
Primary Therapeutic Principle
Move qi, resolve toxin, reduce swelling
Classical Source
Later qi-moving formula
Available as Granules
Yes

Formula Overview

A qi-flowing formula for stagnation with swelling and toxin.

Therapeutic Principle

Selected for qi-stagnation swelling with toxin rather than pure qi stagnation or early excess sores.

Composition: Sovereign, Minister, Assistant, Envoy

Every herb in the formula, grouped by the job it does in the classical hierarchy.

Classical Composition

  • A sixteen-ingredient qi-moving
  • toxin-resolving formula. Common components include Aucklandiae Radix (Mu Xiang)
  • Citri Reticulatae Pericarpium (Chen Pi)
  • Aurantii Fructus (Zhi Ke)
  • Chuanxiong Rhizoma (Chuan Xiong)
  • Angelicae Sinensis Radix (Dang Gui)
  • Paeoniae Radix (Shao Yao)
  • Forsythiae Fructus (Lian Qiao)
  • Lonicerae Flos (Jin Yin Hua)
  • Platycodi Radix (Jie Geng)
  • Glycyrrhizae Radix (Gan Cao)
  • and related qi-moving and resolving herbs. Versions vary.

Dosages follow the classical source and are shown for study, not as a prescription.

Related Conditions

Related Health Topics

Actions

  • Moves qi
  • resolves toxin
  • and reduces swelling.

Indications

  • Qi stagnation with swelling and toxin.

Tongue & pulseSwelling, distension, wiry pulse.

Traditional Pathogenesis

Cause & mechanism

  • Qi stagnation with toxin and swelling.
  • Qi fails to move and toxin accumulates.

Clinical presentation

    Tongue & pulseSwelling, distension, fixed or wandering discomfort, possible sores, wiry pulse.

    Treatment strategy

    • Move qi, resolve toxin, reduce swelling.

    How does this formula compare?

    Compare Shi Liu Wei Liu Qi YinChai Hu Shu Gan SanXian Fang Huo Ming YinYue Ju Wan
    Primary Function Move qi, resolve toxin, reduce swellingCourse Liver Qi, regulate Qi, stop painClear heat, resolve toxin, reduce swelling, invigorate blood, stop painRegulate Qi, resolve stagnation of the Six Constraints
    Formula Category Qi-Regulating FormulasQi-Regulating FormulasHeat-Clearing FormulasQi-Regulating Formulas
    Typical TCM Pattern Qi StagnationQi StagnationDamp-HeatQi Stagnation
    Main Conditions Bloating·Hypochondriac Distension·Skin AcneHypochondriac Distension·Bloating·Emotional Depression·Chest TightnessFever·Sore ThroatChest Tightness·Bloating·Emotional Depression·Poor Appetite
    Main Herbs Aucklandia / Costus Root·Tangerine Peel·Bitter Orange·Chuanxiong Rhizome·Chinese Angelica RootBupleurum Root·Cyperus Rhizome·Chuanxiong Rhizome·Bitter Orange·White Peony RootAngelica Dahurica Root·Fritillaria Bulb·Saposhnikovia Root·Red Peony Root·Chinese Angelica RootCyperus Rhizome·Atractylodes Rhizome·Chuanxiong Rhizome·Medicated Leaven·Gardenia Fruit
    Classical Source Later qi-moving formulaJing Yue Quan Shu (Complete Works of Jingyue, Ming dynasty)Ming-Qing classical formularyDan Xi Xin Fa (Teachings of Zhu Danxi, Yuan dynasty)

    Clinical Perspective

    Shi Liu Wei Liu Qi Yin, Chai Hu Shu Gan San and Xian Fang Huo Ming Yin address stagnation or toxin. Chai Hu Shu Gan San moves liver qi. Xian Fang Huo Ming Yin clears early sores. This formula moves qi and resolves toxin together.

    Clinical Differentiation

    • Used for qi-stagnation swelling.
    • Key points: distension with swelling.
    • Distinct from pure heat-toxin formulas and pure qi-moving formulas.

    Safety notes: Complex formula; not appropriate for pure deficiency or for pregnancy without guidance.

    For educational reference only, based on traditional pattern differentiation — not a substitute for professional advice.

    Frequently Asked Questions

    What is Shi Liu Wei Liu Qi Yin? Are Xiao Yao San and Chai Hu Shu Gan San the same?
    Shi Liu Wei Liu Qi Yin (十六味流气饮) is a classic formula from the Yi Zong Jin Jian, centered on tonifying qi and nourishing blood, regulating qi and dispelling dampness, and dispersing nodules for qi stagnation with Liver constraint and qi deficiency with blood insufficiency in breast lumps, goiter and the like. Xiao Yao San soothes the Liver, strengthens the Spleen and nourishes blood, leaning to Liver constraint with blood deficiency. Chai Hu Shu Gan San soothes the Liver, regulates qi and invigorates blood, leaning to Liver constraint with qi stagnation. The three cannot be interchanged by equal weight. Write Shi Liu Wei Liu Qi Yin. Use caution in excess heat and yin deficiency.
    What is the composition and traditional use of Shi Liu Wei Liu Qi Yin?
    Classic composition: Dang Gui, Chuan Xiong, Shao Yao, Rou Gui, Ren Shen, Zi Su, Jie Geng, Bai Zhi, Huang Qi, Mu Xiang, Wu Yao, Hou Po, Zhi Qiao, Bing Lang, Fang Feng, Gan Cao. It acts to tonify qi and nourish blood, regulate qi and dispel dampness, and disperse nodules. It is used for qi stagnation with Liver constraint and qi deficiency with blood insufficiency in breast lumps, goiter and accumulations. Huang Qi and Ren Shen tonify qi; Dang Gui, Shao Yao and Chuan Xiong nourish blood; Mu Xiang, Wu Yao, Zhi Qiao, Hou Po and Bing Lang regulate qi; Zi Su, Fang Feng, Bai Zhi and Jie Geng disperse nodules; Rou Gui warms and frees; Gan Cao harmonizes.
    How do you choose raw versus prepared? Can Xiao Yao San replace it?
    Huang Qi is raw or honey-fried; Ren Shen is raw. Xiao Yao San lacks heavy regulation of qi and dispersal of nodules; it cannot replace the formula by equal weight. Commercial products follow regulated compounding; do not self-modify.
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    Medical Disclaimer

    For general TCM education only — not medical advice. Consult a qualified TCM practitioner or licensed healthcare provider before use, especially if pregnant, nursing, on medication, or managing a chronic condition.

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