Gui Zhi Jia Long Gu Mu Li Tang

Classical TCM Formula Profile

Part of the HJMEDICAL TCM Discovery Center

桂枝加龙骨牡蛎汤 · Guì Zhī Jiā Lóng Gǔ Mǔ Lì Tāng

A Jin Gui formula based on Gui Zhi Tang with Long Gu and Mu Li, for Yin-Yang disharmony with loss of essence, dream emission, insomnia and a floating deficient pulse.

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Quick Facts

Formula Category
Calm the Shen Formulas
Primary Pattern
Yang Deficiency
Primary Function
Harmonise Yin and Yang, secure essence, calm the spirit
Primary Therapeutic Principle
Regulate Yin-Yang, astringe essence and calm the Shen
Classical Source
Jin Gui Yao Lue (Zhang Zhongjing, Eastern Han)
Available as Granules
Yes

Formula Overview

A Jin Gui formula based on Gui Zhi Tang with Long Gu and Mu Li, for Yin-Yang disharmony with loss of essence, dream emission, insomnia and a floating deficient pulse.

Therapeutic Principle

Traditionally selected for Yin-Yang disharmony with insomnia, seminal loss or sweating from insecurity of essence — a harmonising and astringing formula rather than a pure heat-clearing or pure Yang-tonifying one.

Composition: Sovereign, Minister, Assistant, Envoy

Every herb in the formula, grouped by the job it does in the classical hierarchy.

Classical Composition

  • Ramulus Cinnamomi (Gui Zhi) 9g
  • Radix Paeoniae Alba (Bai Shao) 9g
  • Rhizoma Zingiberis Recens (Sheng Jiang) 9g
  • Fructus Jujubae (Da Zao) 3pcs
  • Radix et Rhizoma Glycyrrhizae Praeparata cum Melle (Zhi Gan Cao) 6g
  • Os Draconis (Long Gu) 15g
  • Concha Ostreae (Mu Li) 15g

Dosages follow the classical source and are shown for study, not as a prescription.

Related Conditions

Related Health Topics

Actions

  • Harmonizes ying and wei
  • settles the spirit
  • and secures essence.

Indications

  • This formula is indicated for ying-wei disharmony with unsecured essence and an unquiet spirit.
  • Signs and symptoms include palpitations, restless sleep, seminal loss or dreaming emission, and abdominal urgency.

Tongue & pulseThe pulse is hollow or moderate.

Traditional Pathogenesis

Cause & mechanism

  • This pattern arises from deficient yang that fails to warm and activate the interior.
  • Without yang warmth, cold collects in the middle or lower jiao, causing cold pain, loose stools, cold limbs and a preference for warmth.
  • Ying-wei disharmony with unsecured essence and an unquiet spirit produces palpitations, seminal loss and restless sleep.

Treatment strategy

  • The correct method is to warm yang, dispel cold, and restore interior activation.
  • In this formula the emphasis is to regulate Yin-Yang, astringe essence and calm the Shen.

How does this formula compare?

Compare Gui Zhi Jia Long Gu Mu Li TangChai Hu Jia Long Gu Mu Li TangSuan Zao Ren TangJin Gui Shen Qi Wan
Primary Function Harmonise Yin and Yang, secure essence, calm the spiritHarmonise Shaoyang, calm the spirit, relieve constraintNourish Blood, calm the spirit, clear heatWarm and tonify Kidney Yang
Formula Category Calm the Shen FormulasCalm the Shen FormulasCalm the Shen FormulasYang-Tonifying Formulas
Typical TCM Pattern Yang DeficiencyQi StagnationBlood DeficiencyKidney Yang Deficiency
Main Conditions Insomnia·Anxiety Restlessness·Spontaneous Sweating·Premature EjaculationAnxiety Restlessness·Insomnia·Chest Tightness·Emotional DepressionInsomnia·Anxiety Restlessness·Dry Mouth & Throat·Night SweatsFrequent Nocturia·Edema·Cold Limbs·Low Libido
Main Herbs Cinnamon Twig·White Peony Root·Fresh Ginger·Jujube / Chinese Date·Honey-fried LicoriceBupleurum Root·Dragon Bone / Fossilized Bone·Oyster Shell·Scutellaria / Baikal Skullcap·Ginseng RootSour Jujube Seed·Poria / Hoelen·Anemarrhena Rhizome·Chuanxiong Rhizome·Licorice RootPrepared Rehmannia Root·Cornus Fruit·Chinese Yam·Poria / Hoelen·Moutan Bark / Tree Peony Bark
Classical Source Jin Gui Yao Lue (Zhang Zhongjing, Eastern Han)Shang Han Lun (Zhang Zhongjing, Eastern Han)Jin Gui Yao Lue (Zhang Zhongjing, Eastern Han)Jin Gui Yao Lue (Zhang Zhongjing, Eastern Han)

Clinical Perspective

Gui Zhi Jia Long Gu Mu Li Tang harmonises and secures for deficiency with floating Yang. Chai Hu Jia Long Gu Mu Li Tang addresses constrained heat with restlessness more strongly. Suan Zao Ren Tang nourishes Blood and calms the spirit for deficiency irritability. Jin Gui Shen Qi Wan warms and tonifies Kidney Yang for deeper Yang deficiency.

Clinical Differentiation

  • Gui Zhi Jia Long Gu Mu Li Tang is used for ying-wei disharmony with unsecured essence and an unquiet spirit.
  • The pattern includes palpitations, restless sleep and seminal loss.
  • Long Gu and Mu Li distinguish it from Gui Zhi Tang.
  • It is distinguished from Chai Hu Jia Long Gu Mu Li Tang, which treats a shaoyang-lingering pathogen rather than a gui-zhi constitution.

Safety notes: This formula is not appropriate when palpitations and seminal loss come from blazing heart or liver fire rather than ying-wei disharmony.

For educational reference only, based on traditional pattern differentiation — not a substitute for professional advice.

Frequently Asked Questions

What are the actions of Gui Zhi Jia Long Gu Mu Li Tang?
Gui Zhi Jia Long Gu Mu Li Tang has the actions of harmonizing Yin and Yang, calming the spirit, and anchoring and astringing. It is Gui Zhi Tang with the addition of Long Gu and Mu Li, used to restore balance when Yin and Yang are unstable and vital substances are leaking.
Which modern diseases is Gui Zhi Jia Long Gu Mu Li Tang suited to?
Modern TCM clinical practice commonly applies it to individuals whose pattern differentiation falls within Yin-Yang disharmony with leakage, including insomnia with vivid dreams or easy startling, palpitations and anxiety of deficiency type, seminal emission or premature ejaculation, spontaneous or night sweating, enuresis, and certain menopausal or neurasthenic presentations with the classical signs.
Is Gui Zhi Jia Long Gu Mu Li Tang suitable for improving seminal emission, lower abdominal tension, and restless sleep?
For presentations of lower abdominal string-like tension or cold sensation in the genitals, seminal emission (in men) or dreaming of intercourse (in women), dizziness, hair loss, palpitations, insomnia with excessive dreams, and a deficient, large, hollow or stirring pulse — in those whose pattern differentiation confirms deficiency taxation with Yin-Yang instability — TCM commonly applies Gui Zhi Jia Long Gu Mu Li Tang as an adjunct. It cannot replace standard medical treatment.
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Medical Disclaimer

For general TCM education only — not medical advice. Consult a qualified TCM practitioner or licensed healthcare provider before use, especially if pregnant, nursing, on medication, or managing a chronic condition.

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